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Histopathological changes in rabbit retinitis pigmentosa

The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...

Postoperative diplopia test with BT for inferior oblique overaction

The authors evaluate a novel assessment of botulinum toxin (BT) injection into the inferior oblique (IO) as a postoperative test in those with secondary IO overaction. This was a retrospective review of 23 injections for 18 patients using 1.25U of...

Enucleation refusal for retinoblastoma

Retinoblastoma is the most common eye cancer in childhood, with enucleation rarely being the only lifesaving surgical option, especially where evidence of extraocular spread is apparent. This study sought to survey a global pool of eye care professionals with regards...

Early diagnosis of pituitary apoplexy using combined MRI findings

The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...

A case series of acquired esotropia in cerebellar disease

Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...

Literature review of isolated ocular motor nerve palsies

Patients aged over 50 presenting with isolated nerve palsies of the third (pupil sparring), fourth or sixth nerves, are often described as having microvascular extraocular palsies. This review looks critically at the evidence surrounding these microvascular non-arteritic extraocular palsies and...

Effect of intravenous mannitol in post vitrectomised eyes

The purpose of the study was to evaluate the effect of intravenous mannitol 20% on intraocular pressure in vitrectomised silicone-oil filled eyes. A prospective analysis of consecutive patients was undertaken with their fellow eyes taken as controls. Thirty-one patients were...

Use of acetazolamide for symptoms of visual vertigo

Visual vertigo is a disorder characterised by symptoms of dizziness, vertigo, unsteadiness, disorientation and general discomfort induced by visual triggers. It is currently treated with vestibular rehabilitation therapy, with no effective pharmacotherapy options available for treatment resistant case. Oral acetazolamide...

IgG4 related orbital disease

This retrospective study was done to determine the prevalence of IgG4 related orbital disease (IgG4ROD) in patients who previously had biopsies for suspected idiopathic orbital inflammatory disease (IOID) and / or orbital lymphoproliferative disease (OLD). The charts and slides of...