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Does methanol poisoning require ophthalmic investigation?

The authors report a case series of 21 patients (41 eyes) diagnosed with acute methanol poisoning following an outbreak in Tunisia in 2020. All patients underwent a complete ophthalmological examination including visual fields, colour vision test and optical coherence tomography...

Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

MPH treatment effect in ADHD on choroidal vascular index

In this study the authors aimed to investigate the choroidal vascular index (CVI) in treatment-free children with ADHD, children regularly taking methylphenidate (MPH) and healthy controls. This was a prospective cross-sectional study of 52 patients with newly diagnosed ADHD, 46...

PAX6 methylation and myopia

The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...

Macular choroidal changes after inferior oblique muscle surgery

This study was undertaken to investigate the retinal neurovasculature, choroidal thickness and choroidal vascular index (CVI) changes at the macula at one week, one- and three-month intervals post inferior oblique muscle myectomy. The hypothesis was that, given the close proximity...

Use of immunomodulatory treatment for non-infectious uveitis: an International

Two-hundred-and-twenty-one group members from 53 countries completed a questionnaire on their indications, investigations and use of conventional and biologics and follow-up of treated patients. Main indications to start systemic immunomodulatory drugs were: uveitis not controlled by oral prednisolone (94.1%), specific...

Traumatic injuries from foam Nerf bullets

Background Three patients are presented in this case report: an adult and two children which were subjected to ocular injuries from Nerf gun bullets. Generally, Nerf guns are considered safer than airsoft guns. While there are many papers on airsoft...

Detecting apoptosis in retinal cells

This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...

Review of non-arteritic anterior ischaemic optic neuropathy

This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...

How to get the most out of your ophthalmology elective

If you are in your penultimate year (or even earlier) and have already decided that you want to do ophthalmology, good for you! Ophthalmology is one of the most competitive specialties, and one of the easiest ways to demonstrate your...

Tackling diabetic retinopathy globally through the VISION 2020 LINKS Diabetic Retinopathy Network

It is abundantly clear that the burden of diabetes is rapidly increasing, as there are now 415 million adults with diabetes in the world, with a projected rise to 642 million by 2040 [1]. This equates to 1 in 10...