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Childhood blindness and visual impairment in the Narayani Zone of Nepal

Up to 50% of childhood blindness is preventable or treatable, and its control is a high priority in the VISION 2020 initiative of the International Agency for the Prevention of Blindness. In this study, the authors utilised the rapid assessment...

Examination of optic disc drusen using computer-based fundus analysis

This case-control study analysed the optic disc angioarchitecture in optic disc drusen (ODD) using computer-based fundus examination. A group of ODD patients were compared to a group of healthy controls with normal optic discs. The cohort included 30 healthy volunteers...

Ozurdex in epiretinal membrane surgery

This was a prospective multicentre pilot study, looking at the effect of Ozurdex on visual acuity (VA) and central retinal thickness (CRT) in patients undergoing surgery for epiretinal membrane (ERM). Twelve eyes of 12 patients were included in the study....

Clinical features of ocular syphilis

The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...

Pupil responses in diabetes

This study aimed to investigate pupillary involvement in patients with type 2 diabetes mellitus (DM) and to evaluate any relationship between severity of diabetic retinopathy (DR) and pupillary responses. Participants included 133 individuals in four groups: proliferative DR (n=21), non-proliferative...

Treatment efficacy of stage 4 ROP

This study aimed to determine the efficacy of combined vitrectomy and anti-VEGF injection for advanced stage 4 ROP with extensive neovascular proliferation (NF). The study included nine infants; six bilateral and three unilateral. Seven were female and the mean gestational...

Visual and refractive outcomes and complications in FLACS versus CPS cataract surgery

This is a randomised, controlled study of 110 paired eyes from 55 patients that were randomised into either femtosecond laser-assisted cataract surgery (FLACS) or conventional phacoemulsification cataract surgery (CPS) groups. Visual, refractive outcomes, intraocular pressure (IOP) and complications were compared...

Relationship between intraocular pressure and optic nerve damage in optic nerve drusen

The authors present a retrospective study exploring the relationship between intraocular pressure (IOP) and optic nerve damage in patients with optic nerve drusen. The aim was to evaluate if patients with normal ocular pressure at the time of optic nerve...

Risk of CNV related to angioid streaks in PXE

This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...

A pulsatile pump in the TM, a new concept in trabecular outflow research

This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...

Complications after cataract surgery in high myopes: a systematic review and meta-analysis

The authors review all the modern literature on complications after phacoemulsification in high myopes with axial lengths (AL) greater than 25.0mm. Twenty-eight studies reporting on 19,586 eyes were included. The corrected distance visual acuity (CDVA) improved from 0.96 ± 0.53...

Combined versus traditional photocoagulation treatment for aggressive posterior retinopathy of prematurity (APROP)

The purpose was to report the outcomes of the combined treatment of sparing laser photocoagulation and intravitreal Bevacizumab (IVB) treatment versus conventional laser photocoagulation intervention in APROP. This was a study of 18 eyes of nine infants. One was excluded...