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Ocular manifestations of Whipple’s disease
2 February 2024
| Lucy Osborne
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EYE - Vitreo-Retinal
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Granulomatous uveitis, Whipple’s disease, infectious uveitis, ocular infection, tropheryma whipplei
In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...
Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
4 August 2021
| Jane Ashworth, Tsveta Ivanova, Susmito Biswas, Assad Jalil, Georgina Hall, Rebecca Redmond, Graeme CM Black (Prof), William Newman, Neil Parry, Jane CB Gray, Charlotte Skitterall
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EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...
Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies
1 October 2018
| Rod McNeil
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EYE - General
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...
RNIB gets ‘izzy-wizzy’ to celebrate Sooty’s 75th anniversary
The Royal National Institute of Blind People (RNIB) celebrates Sooty’s 75th anniversary by launching a new Sooty Collection Box, which has been given a modernised glow-up.Serendipity
3 October 2024
| Peter Cackett
“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...
Papilloedema: an update
1 June 2016
| James F (Barry) Cullen
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EYE - Neuro-ophthalmology
Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...
A guide to utilising your time efficiently to develop clinical and procedural skills as an aspiring ophthalmologist
4 February 2025
| Shaswath Ganapathi
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EYE - General
Ophthalmology often receives limited coverage in the undergraduate medical curriculum, and the availability of foundation programme jobs in this field is also restricted, reducing exposure to this field for aspiring ophthalmologists. Even if you’re not planning to specialise in ophthalmology,...
The power of the full blood count
Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...Reflections on designing and delivering an undergraduate ophthalmology teaching programme
28 March 2023
| Alexander Strother
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EYE - General
Dr Alexander Strother reflects on his time designing and delivering a classroom-based programme to ensure that medical students know how to take comprehensive ophthalmic histories from patients. Working as a clinical teaching fellow, in 2021 I had the great privilege...
An Inconvenient Truth: Pete’s hidden curriculum Part 4
5 June 2023
| Peter Cackett
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EYE - General
“What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The above is a quote attributed to Mark Twain from the 2006 documentary, An Inconvenient Truth, which follows Al...
What's trending Jun/Jul 2021
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #blindpensioner #teachescooking #cookbook Simon Mahoney lost his eyesight to uveitic glaucoma. His wife was his main carer and did most of...What's trending Apr/May 2024
3 April 2024
| Amit Dhalla
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EYE - General
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #GrahamNorton #eyelids Graham Norton’s chat show is always a must-watch in my book. I was particularly surprised to find two eye-related...
