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Leading North London eye clinic appoints retina expert to treat growing ‘epidemic’ of patients living with myopia
Leading independent eye hospital based in Finchley, My-iClinic, has welcomed Consultant Ophthalmologist, Ms Yvonne Luo, to its growing team of specialists.Working smarter not harder: How to transform eyecare delivery in the United Kingdom (part 2)
Are we doing enough to meet the current demands on ophthalmic services? In part two of a two-part series (see Part 1 here), Rosalind Harrison explains how efficiency can be improved by setting up eye services in community hubs. The...
Silicone oil migration presenting as an eyelid cyst
The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...
Resveratrol protects against steroid induced intraocular pressure
Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
Hemianopia or visuospatial neglect: differences in information processing
It is widely reported that visuospatial neglect and hemianopia may be superimposed, and disentangling the two conditions can be pose difficulties for clinicians. The authors of this paper explored the differences in implicit information processing which is effective in patients...
Cataract surgery and circadian photoentrainment
The study authors sought to investigate the possible effects of circadian photoentrainment following cataract. This was a randomised clinical trial, where 76 eyes of 76 patients (with bilateral cataract) were randomised to blue-blocking or neutral intraocular lenses (IOLs). Outcome measures...
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
Intravitreal functional plasminogen in branch retinal vein occlusion
Branch retinal vein occlusion (BRVO) is the second most common vascular disorder of the eye. Intravitreal injections of anti-VEGF agents and corticosteroids have proven efficacy. Posterior vitreous cortex (PVC) adhesion has been shown to support the development of retinal vein...
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
