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CD40L activation of human RPE cells

Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...

Quiz Oct/Nov 2022

History An Afro-Caribbean woman, aged 30, with “scleral tattooing” for cosmetic reasons (subconjunctival dye injection), presented with bilateral upper and lower eyelid oedema for one week, and she also had restricted eye movement and blurry vision in her right eye....

Sutureless, scleral fixated-IOLs

This was a retrospective cohort study of 112 sutureless, scleral-fixated posterior chamber intraocular lens implantations (SSFCIOL) over a four-year time period. Mean follow-up duration was 13.0 ±10.4 months. The primary indication for SSFCIOL was dislocation of IOL due to zonular...

Eye Capacity: clinical need should drive ophthalmic service provision

Almost two million people in the UK suffer sight loss, a number forecast to double over coming decades. Major causes of blindness are age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, cataract and uncorrected refractive error. Prevalence of these sight-threatening conditions...

Binocular summation responses in strabismic amblyopia

A preliminary study was conducted to determine whether binocular summation (BS) in strabismic amblyopia is more decreased than in strabismus alone and whether strabismus surgery improves BS. The study included 15 strabismic amblyopes, 30 normal controls and 30 strabismic controls....

Braille at 200: The code that changed everyday life

Frenchman Louis Braille was in his teens in the mid-1820s when he began developing the six-dot tactile code that enables millions of blind and partially sighted people around the world to access the power of literacy. Two centuries on from...

My top five: A foundation doctor’s top five misconceptions about ophthalmology

Choosing a specialty is challenging. As a foundation doctor, it often feels as if this choice is based solely on fleeting experiences. Compared to other specialties, there is relatively little exposure to ophthalmology during either medical school or foundation years....

My Top Five: A foundation doctor’s top five misconceptions about ophthalmology

Choosing a specialty is challenging. As a foundation doctor, it often feels as if this choice is based solely on fleeting experiences. Compared to other specialties, there is relatively little exposure to ophthalmology during either medical school or foundation years....

Should points for simulated surgery be removed from the ophthalmology ST1 evidence folder?

The benefits of the Eyesi surgical simulator by Haag-Streit UK for early career ophthalmology speciality trainees are well-established, allowing for the practice of cataract and vitreoretinal surgery in a controlled, risk-free environment. Whilst the Eyesi is an invaluable resource for...

CHEC announces launch of two new treatment centres (1)

New sites in Ilford and Milton Keynes will further extend CHEC’s community-focused endoscopy and ophthalmology services across England.

Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus

In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...

Portable corneal topography – exploration of a prototype

Ophthalmic imaging devices, such as corneal topographers, are not widespread in the developing world. A small device that connects to a smartphone might be a solution to improve developing nation access to corneal imaging. I recently had the opportunity to...