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Cancer associated retinopathy
Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...Sustainability in ophthalmology and healthcare: An overview
Finally, even staunch sceptics are coming around to recognising that climate change is real and that we should do something about it. But how proximal the threat is and at what pace change has to happen is not universally agreed...My top five: Trinkets of fact or fiction
Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...My Top Five: Trinkets of fact or fiction
Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...Quiz Jun/Jul 2024
History A one-year-old girl originally presented with a red eye, initially bilaterally and later in the left only. On examination a membrane was found on the tarsal conjunctiva of the upper eyelid (Figure 1). Figure 1: Anterior segment. Serum plasminogen...Artificial intelligence and oculomics: Improving global health
The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...
Prevalence of strabismus in neurofibromatosis type 1
The purpose of this study was to evaluate the prevalence of strabismus in NF1 by comparing children with normal neuroimaging to those with optic pathway glioma. The study included 236 children with NF1, of which 38 were excluded with no...Birdshot chorioretinopathy: an important differential
Birdshot chorioretinopathy (BSCR) is a relatively uncommon cause of posterior uveitis which often has a relapsing and remitting course [1,2]. We present a case which demonstrates how remission can be obtained for several years using cyclosporine. Case report A 44-year-old...
