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Effects of blood donation on the physiology of the eye
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
Prediction of visual outcome in IIH
In this prospective study, visual outcome of 40 patients with idiopathic intracranial hypertension (IIH) was compared with clinical and neuro-ophthalmic parameters. The purpose of this was to determine any correlation to try and predict visual outcome for IIH patients. Parameters...
Is exenteration helpful in invasive fungal sinusitis?
Invasive fungal sinusitis is a potentially lethal disease that causes painful orbital apex syndrome with ophthalmoplegia and visual loss. The mechanism of ophthalmoplegia and visual loss is not clear, and neither is the role of radical surgery-orbital exenteration. The authors...
Recognising clinical characteristics of blepharospasm
Focal dystonia is regarded as a characteristic feature of blepharospasm, but patients do not always present with these motor symptoms. The authors present a retrospective analysis of data from a large number of patients treated for drug-induced or essential blepharospasm...
Biopsy of nasolacrimal duct using sheath guided dacryoendoscopy
In this study the author’s biopsied six eyes of five individuals with recurrent nasolacrimal duct obstruction following a prior dacryoendoscopic probing. All procedures were performed under local anaesthetic, the obstruction or lesion was directly visualised with dacryoendoscope and biopsy was...
Efficacy of IVC injection in the treatment of ROP
This is a retrospective consecutive case series of patients who received intravitreal conbercept (IVC) as a primary treatment from June 2015 to July 2016 for treatment of retinopathy of prematurity (ROP). Forty-eight eyes of 24 patients were included in the...
Prevalence of strabismus in neurofibromatosis type 1
The purpose of this study was to evaluate the prevalence of strabismus in NF1 by comparing children with normal neuroimaging to those with optic pathway glioma. The study included 236 children with NF1, of which 38 were excluded with no...
Prognostic factors for visual acuity in patients with LHON after gene therapy
This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...
A novel way to diagnose optic neuropathies using Bruch’s membrane opening
Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...
Clinical features of ocular syphilis
The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...
Profile of sympathetic ophthalmia (SO)
The authors undertook this study to examine the clinical profile of patients aged <18 years with SO over the past 20 years. This was a hospital-based retrospective study from 1997 to 2017. SO is a diagnosis of bilateral panuveitis following...
