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Autophagy in lens mitochondria loss
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
A case report of cavernous sinus syndrome following dental procedure
This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
CAT-QoL questionnaire
The purpose of this study was to use Rasch analysis to inform the refinement of the CAT-QoL amblyopia treatment questionnaire. Of the 342 subjects that were recruited across nine centres, 315 had sufficient clinical data for analysis with RUMM software....
Use of group consultations in the management of idiopathic intracranial hypertension
The incidence of idiopathic intracranial hypertension (IIH) has risen by >100% between 2002 and 2016 in the UK, in association with rising obesity rates. This increasing incidence has inevitably led to increased pressures on service capacity. Evidence for other conditions...
