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Association of asthenopia and heterophoria
Heterophoria varies over time and asthenopic symptoms may be greater when the heterophoria is larger. Thus a close intra-individual correlation may exist between heterophoria and discomfort during reading. The authors investigated the variability of both parameters in 20 individuals who...
Limbal melanocytes and the stem cell niche
The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...
Association between colour vision impairment and amyotrophic lateral sclerosis (ALS)
The purpose of this study is to test the hypothesis that colour vision impairment is associated with amyotrophic lateral sclerosis (ALS). Abnormalities of the inner and intermediate retinal structures in patients with ALS have been described using optical coherence tomography...
IXT control vs. binocular summation
The purpose of this study was to evaluate the relationship of BS scores with other current markers used for evaluating the control in preoperative intermittent exotropia (IXT) patients. Data was collected on stereoacuity, angle of deviation, Newcastle control score (NCS),...
A mouse model for uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Investigation of blood platelet parameters in anterior ischaemic optic neuropathy
The aim of this clinical retrospective comparative study was to assess the possible relationship between arteritic anterior ischaemic optic neuropathy (AAION) and non-arteritic anterior ischaemic optic neuropathy (NAION) with blood platelet parameters and neutrophil-to-lymphocyte ratio (NLR). The medical records of...
Test combination which could detect prodromal Alzheimer disease
The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...
Comparison of visual acuity testing in clinic versus at home
The authors present a prospective cohort study including children aged three to 12-years-old with and without ocular pathology. Visual acuity was assessed using both an M&S Smart System in clinic, using different protocols depending on the age of the child....Building research capacity through the VISION 2020 LINKS Programme
The aim is to build capacity for research in the region covered by the College of Ophthalmology of Eastern, Central and Southern Africa (COECSA). The project will build research capacity in three ophthalmology training institutions by ‘training the trainers’ and...
