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Two-year interim safety results of the 0.2ug/day FAC intravitreal implant for the treatment of DMO
This is a 24-month interim prospective observational study of 95 previously steroid challenged patients (115 eyes) receiving intravitreal 0.2ug/day fluocinolone acetaid (FAC) implant for diabetic macular oedema (DMO) treatment. The mean IOP for pre- and post- FAC implants were stable,...
Foveal displacement after macular hole surgery
Previous studies show that internal limiting membrane (ILM) peeling during macular hole surgery is associated with retinal shrinkage (microtubule depolymerization of the axons of the inner retina) and nasal shift of the fovea. A temporal inverted ILM flap technique was...
Hess vs. Harms vs. PCT measurements
This study aimed to compare the results of the different tests in 36 strabismus patients and 18 healthy controls aged 6-81 years. Tests included alternate prism cover test, Hess screen and Harms screen. Because of glasses restrictions with the Harms...
Aflibercept (AF) for age-related macular degeneration (ARMD): four-year outcomes of a ‘’treat-and-extend’ (T&E) regimen with exit-strategy
This is a retrospective observational study of 82 patients, between 2014 to 2016 from Switzerland of treatment-naive patients with nARMD, treated with AF, with specific T&E protocol without a loading phase and predefined exit criteria and patients were observed three...
Depth and width of corneal wounds post corneal foreign body removal
This was a prospective study of 63 eyes of 63 patients undergoing corneal foreign body (FB) removal with a 27G needle at the slit-lamp; 96.8% of the patients were men with mean age 35.8 ±11.0 years. Regarding location of FBs,...
Outcomes of chemo versus no therapy for optic pathway glioma in NF1
The aim of this study was to evaluate the visual outcomes of a cohort of children with optic pathway gliomas and neurofibromatosis type 1 (NF1), with comparison of children treated with chemotherapy or not. This was a retrospective study of...
Assessing possibility of deferring lumbar puncture in mild idiopathic intracranial hypertension
This was a retrospective review of patients consecutively presenting with idiopathic intracranial hypertension (IIH) to a tertiary neuro-ophthalmology clinic without a lumbar puncture (LP) over an eight-year period. Inclusion criteria included true optic disc oedema, retinal nerve layer thickness ≤300µm,...
Visual outcomes and predictors in optic pathway glioma
This is a retrospective study of 60 paediatric optic pathway glioma (OPG) patients (NF1 or sporadic) presenting to Great Ormond Street between 2003-2017. Median follow-up was 82 months. Analysis was divided into best and worst eye vision representing level quality...
Using bupivacaine to the medical rectus in addition to lateral rectus recession for convergence insufficiency type intermittent exotropia
This is a retrospective study of 60 paediatric optic pathway glioma (OPG) patients (NF1 or sporadic) presenting to Great Ormond Street between 2003-2017. Median follow-up was 82 months. Analysis was divided into best and worst eye vision representing level quality...
Brolucizumab in age-related macular degeneration, HAWK Study
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
Bromfenac versus betamethasone in diabetic macular oedema
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
