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RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

Nanoparticle administration of latanoprost

Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...

Tetracaine to reduce OCR

This study investigates the effects of Tetracaine eye drops on oculocardiac reflex (OCR) during strabismus surgery. A randomised controlled trial of 70 strabismus surgery patients aged two to 19 years was conducted with comparison of Tetracaine versus placebo. Demographics were...

What's trending Jun/Jul 2018

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #BusyPhillips #photokeratitis #sunglasses Last time, we were in the throes of the Beast from the East. Here in the UK, it’s...

Google Maps - some supremely useful features

This article covers some less well known, yet very useful, features of Google Maps. Estimate your journey time by the day and time you’ll be travelling It’s easy to type a destination in and get an idea about how long...

Air or SF6 in DMEK

This retrospective study compared descemet’s membrane endothelial keratoplasty (DMEK) outcomes in 136 consecutive eyes of 68 patients. All patients underwent DMEK for Fuch’s endothelial dystrophy, where consecutive eyes received 100% air bubble during first eye surgery and 20% sulphur hexafluoride...

Avoiding pre-placed recti sutures in enucleation

This is a retrospective review of 40 patients who underwent enucleation using a non-conventional technique in which the recti muscles were detached from the sclera without pre-placing any sutures to secure the cut muscle ends. The surgery was only performed...

Effect of topical diclofenac on postoperative PRK pain: RCT

A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...