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ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Strabismus and binocular summation
The authors conducted a pilot study to investigate the effect of visual noise or background complexity on binocular summation in patients with strabismus. A target embedded in pixel noise was used. The study involved performance of a task detecting a...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...An arm and a leg
“It cost me an arm and a leg.” – Mr B told me. An arm and a leg to be seen by the famous Russian eye surgeon who said that everybody can be spectacle-free. He took Mr B’s money (roughly...Herpes zoster ophthalmicus: the essentials
Herpes zoster, also referred to as shingles, is a common infection most typically caused by the reactivation of varicella zoster virus that lies dormant (sometime for decades) in the dorsal root nerve ganglion following primary chickenpox infection [1]. In 10-20%...A comparison of light sources in retinal imaging
Before starting to talk about the light sources present in retinal imaging, it is necessary to start from the base: the light. Light is an electromagnetic wave whose smallest part is the photon (or quantum of light). A high frequency...National Usher Syndrome Helpline launched to provide one-stop support for people with Usher syndrome
Deafblind UK and Deafblind Scotland have announced the launch of a new Usher Syndrome Helpline, a dedicated national support service for people living with Usher syndrome and for families, carers and professionals supporting them. Launched by the charity partnership on...Diary from my elective: a Parisian experience
The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...
Superior oblique sagittalisation
This paper reports two cases with anomalous posterior course of the superior oblique tendon with insertion nasal to the superior rectus tendon. Both presented with Brown syndrome-like clinical scenarios. The cases were a five-year-old female and four-year-old male. Diagnosis was...
