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Risk factors for visual impairment in facial nerve palsy

Facial nerve palsy (FNP) is known to be associated with corneal exposure due to the nature of the condition, but how many of those will go on to develop severe visual impairment (SVI)? This study investigates the risk factors associated...

Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study

This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...

Changes in extraocular muscle after the Faden procedure – animal histopathology model

The authors studied the histological changes in the anterior part of the posterior fixation suture including the myoscleral junction, after the Faden operation in eight rabbits. The Faden operation was undertaken in one eye and the fellow unoperated eye served...

Retrospective analysis on the outcomes of contact lens-associated keratitis in a tertiary centre

This is a retrospective cohort study of 161 eyes (153 patients) with contact lens-associated keratitis (CLAK) from Moorfields Hospital between 1 July 2021 to 28 February 2022. They were classified into three groups based on the size of the epithelial...

Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients

This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...

Anti-VEGF agents treatment outcomes in macular telangiectasia

This article is a review of a systematic literature search on Ovid MEDLINE, Embase, and Cochrane Library, from inception to June 2024 for comparative studies on anti-VEGF agents in macular telangiectasia (MacTel). The primary outcome was the change in best-corrected...

Enter the Dragons’ Den: Bob Gokani

I have often daydreamed about inventing a successful new product and then going on to pitch for investment on Dragons’ Den, with the TV show’s seasoned entrepreneurs all competing with each other to invest in my company. My imagined fantasy...

Enter the Dragons’ Den: Bob Gokani

I have often daydreamed about inventing a successful new product and then going on to pitch for investment on Dragons’ Den, with the TV show’s seasoned entrepreneurs all competing with each other to invest in my company. My imagined fantasy...

Could the sclera be key to glaucoma?

The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

Unilateral central scotoma following dengue fever

Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...

Large-scale study uncovers demographic and sex factors behind genetic cause of age-related visual loss

A new study has identified a major genetic contributor to Fuchs’ Endothelial Corneal Dystrophy (FECD), a common cause of vision loss, also highlighting the significant roles of sex and ancestry. FECD is a common, inherited eye condition that primarily affects...

Best way to detect glaucoma progression: by reflecting on the past 25 years

Glaucoma – a condition of optic neuropathy leading to progressive visual field loss often associated with raised intraocular pressure. It is fair to say that our definition for this condition has remained unchanged over the last 25 years and the...