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Differential inhibition of EAU by CTLA4 and IL-6

1 February 2016 | Graham Wallace | EYE - Vitreo-Retinal

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

MicroRNA mediate retinoblastoma signal transduction

1 October 2014 | Graham Wallace | EYE - Vitreo-Retinal

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

Scheimpflug vs. OCT in measuring corneal thickness

1 February 2014 | Brian Ang | EYE - Cornea, EYE - General

The authors report on the reproducibility and repeatability of corneal thickness measurements using three different Scheimpflug imaging cameras (Pentacam, Sirius and Galilei) and one Fourier-domain optical coherence tomography (OCT) system (RTvue-100). The rationale for this study is that corneal thickness...

Screening accuracy

1 December 2018 | Fiona Rowe (Prof) | EYE - Paediatrics, EYE - Strabismus

In this study the authors observed whether and how well orthoptic tests are performed by non-orthoptists in a screening setting. They assessed the quality of screening tests by semi-structured observations of youth health care (YHC) physicians who screened children aged...

Leading North London eye clinic appoints retina expert to treat growing ‘epidemic’ of patients living with myopia

21 November 2023 | My-iClinic, myopia, Yvonne Luo, vitrectomy, floaters

Leading independent eye hospital based in Finchley, My-iClinic, has welcomed Consultant Ophthalmologist, Ms Yvonne Luo, to its growing team of specialists.

NHS Practitioner Health: Providing you with the care you deserve

15 April 2025 | Helen Garr | EYE - General | Wellbeing

Healthcare professionals carry a unique weight: the responsibility for the lives and wellbeing of others. But who takes care of the caregivers? For over 15 years, NHS Practitioner Health has been doing just that – providing vital mental health and...

Embracing assistive technology in the fight against sight loss

10 June 2020 | Julian Jackson | EYE - General

The author shares his own experience of sight loss and explains the vital role assistive technology can play in the lives of visually impaired patients. There is no doubt that sight loss continues to be a clear and present danger,...

My neuro-ophthalmology elective: Weill Cornell Medicine

3 June 2026 | Arslan Raja | EYE - Neuro-ophthalmology

First and foremost, it’s important to evaluate the reasons for pursuing a clinical elective in the US. Personally, I had been set on completing my specialty training (residency) in the US since my third year of medical school, and an...

Navigating challenges and embracing growth

5 December 2025 | Chanelle Smith | EYE - General

Embarking on a career in ophthalmology is both exhilarating and challenging. Moving through the various stages of training, from foundation years to specialty training, brings a steep learning curve and intense demands, often necessitating significant adaptations in both professional and...

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