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Evaluation of the association between diabetes autoantibodies and development of early diabetic retinopathy in type 1 diabetes

This study was conducted to investigate the relationship between diabetes autoantibodies and the development of early diabetic retinopathy (DR) to assess the role of autoimmunity in retinopathy. The study included 18 boys and 44 girls with type 1 diabetes mellitus...

Chandelier-assisted versus standard scleral buckling for rhegmatogenous retinal detachment repair. Systematic review and meta-analysis

Despite a significant global decline in standard scleral buckling (SSB) procedures for rhegmatogenous retinal detachment (RRD), it continues to hold its place as an essential treatment option, offering distinct advantages such as cost-effectiveness, preservation of the vitreous, improved final visual...

Clinical evaluation of a multifocal aspheric diffractive intraocular lens

This is a multi-centre prospective study involving five different centres in Europe including 52 patients with cataract. The average age was 68.5±10.5 years, 35 females were bilateral implanted with aspheric diffractive multifocal lens implantation of the Tecnis 1-Piece multifocal intraocular...

Herpes zoster ophthalmicus: a clinician’s perspective

Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

Dr William Mackenzie: a founding figure of modern ophthalmology

The author looks at the career of William Mackenzie and the important role he played in establishing the status of ophthalmology as a recognised medical speciality. There are certain individuals who, blessed with ability and means, are destined to leave...

Major grant secured to transform immune cell imaging research

A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...

Decoding the red eye

Red eye, or hyperaemia, is one of the most common presentations to primary care [1] and the emergency department [2]. However, despite this the underlying cause is often misdiagnosed which can lead to severe, sight-threatening conditions being missed [1]. Thorough...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

Radiotherapy for orbital apex cavernous haemangiomas

This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....

Providing primary eyecare services during a global pandemic: the new normal

It would be fair to say that 2020 hasn’t quite turned out to be the year that anyone predicted. Living with a global pandemic has become our reality and we are having to get used to many aspects of our...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Grading of ocular inflammation in uveitis: an overview

Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...