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2535 results found

Tacrolimus for endothelial rejection

This double-blinded randomised controlled trial tested the use of adjuvant topical Tacrolimus drops in cases of acute endothelial rejection in penetrating keratoplasty (PK). Patients with typical signs of endothelial rejection were randomised to receive either steroid therapy with topical Tacrolimus...

Non-arteritic anterior ischaemic optic neuropathy in the Asian population

This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...

Sclerotomy suturing

This was a retrospective review of 589 consecutive cases of patients who underwent 23-gauge tranconjunctival pars plana vitrectomy. Cases were split into Type 1 vitrectomies (macular hole, ERM and simple vitreous haemorrhages) and Type 2 cases which were more complex...

Intracameral bevacizumab as an adjunct to trabeculectomy

This is a 12-month, prospective, randomised, double-masked, placebo-controlled trial of patients who were not controlled medically with open angle glaucoma and scheduled for a primary trabeculectomy. Patients were recruited and randomised during the period between April 2009 and November 2010....

Evaluation of keratometry with a novel colour LED corneal topographer

The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...

Subthreshold micropulse laser in BRVO

The purpose of this retrospective, consecutive, single-centre, non-randomised, and case-control study was to verify the therapeutic effects and safety of oedema (from branch retinal vein occlusion (BRVO)) recurrence suppression effect using 577-nm subthreshold micropulse laser photocoagulation (SMLP) in combination with...

Aspirin and upper lid surgery

This is a double-blind randomised controlled trial of preoperative aspirin versus placebo in patients undergoing upper lid blepharoplasty or ptosis surgery. All enrolled patients were already taking aspirin and no other anti-platelet or anticoagulant drugs. All patients either had no...

PI drops and respiratory change during surgery

Five percent povidone-iodine (PI) topical application to the eye has been observed to cause apnoea under general anaesthetic (GAS). The authors designed a randomised single-blinded controlled trial to evaluate changes in respiration caused by PI eye drops. They recruited 100...

Outcomes of early versus late surgery for infantile esotropia

The authors aimed to provide a better understanding of the clinical spectrum of infantile esotropia by comparing motor and sensory results in the long-term follow-up of patients who underwent surgery. This was a retrospective review over a 17-year period. There...

Long-term effect of YAG LPI on corneal endothelium in PACS

This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...

Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG

This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...

Acromegaly associated with enlargement of extraocular recti muscles

This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....