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Handheld OCT in children with Down’s syndrome

1 December 2022 | | EYE - Paediatrics, EYE - Strabismus
This article investigated the use of handheld optical coherence tomography (OCT) in children with Down’s syndrome. Fourteen children were recruited to the study with a mean age of 6 years and 10 months with 57% male. All patients were dilated....

Supranuclear ocular motility disorders

1 June 2022 | | EYE - Neuro-ophthalmology, EYE - General
Figure 1: Bilateral INO Introduction Complex ocular motility disorders are a diagnostic challenge. These patients come with very complex ocular motility presentations and require a careful and detailed assessment in order to find the correct diagnosis and arrange appropriate investigations....
American Journal of Ophthalmology cover image.

Near-infrared autofluorescence to diagnose retinal laser injuries

2 December 2019 | | EYE - Vitreo-Retinal
This retrospective observational case series aimed to assess whether near infrared autofluorescence (NIR-AR) imaging is a useful imaging modality in the diagnosis of hand-held laser retinal injuries. Twelve patients from two centres underwent ophthalmic assessment and retinal imaging including fundus...

Artificial intelligence and oculomics: Improving global health

2 June 2025 | | EYE - Imaging
The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....

Insights from the ‘Rb-NET Challenges’ Session: Evolving approaches in global retinoblastoma management

2 April 2025 | | EYE - Paediatrics, EYE - Pathology, EYE - Oncology
The Retinoblastoma Network (Rb-NET) Multidisciplinary Team (MDT) platform, developed by the London School of Hygiene & Tropical Medicine (LSHTM) and Professor Ido Didi Fabian, is a web-based telemedicine initiative that regularly hosts virtual MDT meetings focused on the evaluation and...

Refined glaucoma referral practice offers prospect of improved capacity and expanded role for primary eye care professionals

1 February 2018 | | EYE - Glaucoma
Glaucoma is the most frequent cause of irreversible blindness worldwide and the second leading cause of blindness in the UK [1,2]. The global prevalence of glaucoma in 2010 was approximately 3.5% for people aged 40-80 years, according to Jonas et...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | EYE - Paediatrics, EYE - Vitreo-Retinal, EYE - General
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Non-infectious Uveitis: Well Known, Weird and Wonderful meets You, Me and the Balloons

3 August 2023 | | EYE - Vitreo-Retinal
Installation view from Manchester International Festival 2023 exhibition Yayoi Kusama: You, Me and the Balloons at Aviva Studios. Images © David Levene. On an uncharacteristically salubrious 5 July 2023, the date of the 75th Anniversary of the UK’s NHS, a...

Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

1 October 2018 | | EYE - General
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

3 April 2023 | | EYE - General
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Intravitreal injections delivered by ophthalmic clinical nurse specialists

1 June 2015 | | EYE - Vitreo-Retinal
Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...

Viral conjunctivitis and COVID-19

23 March 2020
A joint statement was released by the Royal College of Ophthalmologists and College of Optometrists on 19 March.