You searched for "impairment"

2153 results found

Impact of preop occlusion on surgical outcome

The purpose of this study was to evaluate the effect of improved control with part-time occlusion treatment on the final postoperative surgical outcome in patients with intermittent exotropia. Eighty-nine patients were recruited who had unilateral lateral rectus recess / reset...

Prognostic factors for visual acuity in patients with LHON after gene therapy

This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...

The Wachter Review

Professor Robert Wachter (pronounced Wokter) is well known in the NHS IT sector. In late 2015 Jeremy Hunt announced he had tasked Dr Wachter to lead a review of the digital future of the NHS. The resulting Wachter Review was...

Seeing the Funny Side: Taking on the Edinburgh Fringe with Sight Loss

Comedian Jake Donaldson is partially blind, or partially sighted, depending on your outlook on life, but what’s it really like to be a visually impaired comedian?

Risk factors for non-arteritic ischaemic optic neuropathy in an Asian population

The authors reviewed the medical records of 45 Korean patients with non-arteritic anterior ischaemic optic neuropathy (NAION) and 45 healthy controls, in order to determine risk factors for the condition in an Asian population. Previous studies looking at risk factors...

Change in infantile exotropia

This study investigated the clinical course of patients with infantile exotropia who initially presented with a small exo deviation of 10-18 prism dioptres. Eighty-six patients were reviewed: 35 with follow-up of >2 years without surgery and 51 with surgery. The...

Statins inhibit TGFβ2 mediated fibrotic response in astrocytes

Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...

Molecular genetics of achromatopsia

Achromatopsia is a rare autosomal recessive disorder of the cone photoreceptors. Typical characteristics of affected patients include the inability to distinguish colours, impaired visual acuity, photophobia and nystagmus. The condition is said to be more frequent in the Pingelapese population...

Macular pigment and dark adaptation in older population with normal maculas

Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...

Knobby eye syndrome

This study used high resolution MRI to demonstrate and evaluate globe shape in axial high myopia and identify and characterise those with prominent equatorial staphylomata that deflect extraocular muscle paths and presumably alter motility patterns in strabismus. The study included...

Where along the vergence pathway is affected by Parkinson’s Disease?

The authors outlined three hypothesis for the effect Parkinson’s Disease has on blur- and disparity-driven vergence with reference to location within the vergence system that is affected to be tested in this prospective study. The study recruited 14 participants with...

Review of paediatric open globe injuries in the US

This study used the Nationwide Inpatient Sample (NIS) database to describe the trends in types, demographics and incidence of paediatric open globe injuries in the US. The NIS database covers about 97% of the US population and about 20% of...