You searched for "neurological"
Structural effects of migraine on the retina
1 June 2015
| Claire Howard
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EYE - Neuro-ophthalmology
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Migraine, retinal nerve fibre layer thickness, spectral-domain optical coherence tomography
Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...
Selection of visual field test for detection of pituitary disease
This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...Surgical results in spinocerebellar ataxia (SCA)
Patients with SCA frequently develop ocular motility abnormalities including nystagmus, abnormal smooth pursuits, dysmetric saccades, divergence paresis and ophthalmoplegia. Incidence of diplopia is higher in SCA type 3. The purpose of this study was to evaluate surgical responses and outcomes...Large series profiling skew deviation
3 June 2021
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
A retrospective notes review was completed for patients identified as having skew deviation. The authors outline their exact definition of skew deviation within the methods of the paper. One hundred and fifty-seven patients were identified, it is not clear over...
How a paediatric population presented with diplopia
The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...Long-standing flattening effects on the globe following spaceflight
1 December 2021
| Claire Howard
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EYE - Neuro-ophthalmology
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SANS, astronaut, hyperopic shift, international space station (ISS), long-duration space flight (LDSF), visual changes
Posterior globe flattening has been well-documented in astronauts both during and after long-duration spaceflight (LDSF). This globe flattening is thought to be due to the disc centred anterior forces created by elevated volume and / or pressure within the optic...
ROPPVAL Syndrome as a differential diagnosis to optic neuritis
1 December 2021
| Claire Howard
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EYE - Neuro-ophthalmology
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Photophobia, ROPPVAL, headache, migraine, optic neuritis, retro-ocular pain
Optic neuritis (ON) is a common cause of visual loss in young patients. Patients with eye pain and ipsilateral visual loss are often referred into neuro-ophthalmology clinics with a possible diagnosis of ON. In 2018 Jefferis et al. reported a...
Test combination which could detect prodromal Alzheimer disease
2 August 2022
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...
Using perimetry to support lesion location in the retrochiasmal visual pathway
3 April 2023
| Lauren R Hepworth
The authors present a retrospective case review of patients with homonymous hemianopia from a 30-year period. Inclusion criteria included completion of perimetry within two years of diagnosis and a MRI brain. Data extracted from the records included demographics, diagnosis details...
Single case report of horizontal gaze paresis due to medial pontine haemorrhage
9 August 2023
| Claire Howard
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EYE - Neuro-ophthalmology
The authors report a single case (80-year-old female) of bilateral horizontal conjugate gaze palsy due to a dorsal median pontine haemorrhage. The patient presented with skew deviation, bilateral horizontal conjugate gaze palsy, vertical gaze palsy, ipsilateral lower motor neuron facial...
Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma
The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...Visual snow syndrome: a review
11 January 2024
| Ivan Yip
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EYE - Neuro-ophthalmology
Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...