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Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis

22 August 2023 | moorfields, Parkinson's disease, Siegfried Wagner, Pearse Keane, UCL Institute of Ophthalmology, early detection
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.

In conversation with Fares Antaki: The retinal age gap in schizophrenia

3 April 2026 | | EYE - Vitreo-Retinal
Fares Antaki. Nima Ghadiri (NG): The ‘retinal age gap’ (RAG) is a relatively new concept. Based on your study [1], how confident are you in proposing this as a non-invasive, accessible biomarker for accelerated biological ageing in patients with neuropsychiatric...

Strengthening the signal: Advancing oculomics research for systemic health insights

4 December 2024 | | EYE - Imaging
Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...

Oculomics and Big Data changes the game for Medical Ophthalmologists

25 September 2023 | | oculomics, Nima Ghadiri, big data, ai, artificial intelligence, RETFound, Alastair Denniston
Oculomics and Big Data changes the game for Medical Ophthalmologists, and here's why.

In conversation with Robert MacLaren

2 December 2019 | EYE - Vitreo-Retinal, EYE - General
Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

1 December 2015 | | EYE - Neuro-ophthalmology
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

Oculogyric crisis with B12 deficiency

1 June 2022 | | EYE - Neuro-ophthalmology, EYE - Imaging, EYE - General
An oculogyric crisis (OGC) is a dystonic movement disorder of the eyes which can last from seconds to hours. Although there is no published diagnostic criteria for OGC, typically the onset is acute, and it is characterised by conjugate upward...

Artificial intelligence and oculomics: Improving global health

2 June 2025 | | EYE - Imaging
The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....

AI & Oculomics: a new section for Eye News

2 February 2024 | | EYE - General
Inaugurating this new regular section on the exciting landscape of AI and oculomics, we provide an overview which delves into the historical context and the etymology of this field, reviews the current state of play and contemplates possibilities and hopes...

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

1 April 2016 | | EYE - General
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Corporate M&A pace gathers momentum

1 October 2019 | | EYE - General
Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

Eye research: where next?

1 December 2017
Eye research in the UK is underfunded relative to other areas of medical research and general awareness of sight loss and its prevention remains poor, messages that were reinforced in presentations and discussions during a recent research summit meeting in...