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Four year outcomes of macular degeneration treated with ranibizumab
The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...
Intravitreal Ziv-Aflibercept: safety analysis
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...
Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...Moorfields implementing a non-medical intravitreal injection service
This highly sought after intravitreal injection course has had a national and global impact by enabling numerous institutions to establish their own non-medical delivered IVT injection services. With an increasing demand in treatment for people with eye conditions such as...Moorfields: Implementing a non-medical intravitreal injection service
This highly sought after intravitreal injection course has had a national and global impact by enabling numerous institutions to establish their own non-medical delivered IVT injection services. With an increasing demand in treatment for people with eye conditions such as...Moorfields: Implementing a non-medical intravitreal injection service Nov
This highly sought after intravitreal injection course has had a national and global impact by enabling numerous institutions to establish their own non-medical delivered IVT injection services.
G-CSF intravitreal injections for NAION: a pilot study
In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...
5-FU in cicatricial conjunctivitis
This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...
DALK as an early therapeutic option for Acanthamoeba keratitis
Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...
