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Uveitic glaucoma

The purpose of this retrospective study from two tertiary Institutions in Israel over a period of 13 years, is to present the long-term outcomes of uveitic glaucoma and to identify risk factors for progression. The study included 34 patients (53...

Systemic anti-inflammatory versus fluocinolone acetonide intraocular implant

In the Multicenter Uveitis Steroid Treatment (MUST) trial, 255 patients with intermediate uveitis, posterior uveitis or panuveitis were randomised to either fluocinolone acetonide intraocular implant or systemic corticosteroid therapy which was supplemented with immunosuppression if required. Patients were followed up...

Intravitreal triamcinolone for uveitic macular oedema

This paper from South Korea reports on a prospective, double blind, randomised clinical study designed to evaluate the additional benefit of intravitreal triamcinolone (TA) administration for noninfectious uveitic macular oedema as an adjunct therapy to systemic anti-inflammatory treatment. Patients were...

All you need to know about PIC

This is a review article of punctate inner chorioretinopathy (PIC). The authors detail the epidemiology and clinic presentation of the disease. They recognise the challenge of an accurate diagnosis due to its resemblance to other posterior uveitic entities. Multimodal imaging...

Intraocular Inflammation

Intraocular Inflammation is an encyclopedic treatise on uveitis. The editors have invited several experts in the field to author different chapters and provide the reader with an excellent repository of knowledge, experience and evidence on the subject. The approach to...

Clinical features of ocular syphilis

The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...

Epiretinal membranes in uveitic macular oedema

Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...

Diagnostic procedures in vitreoretinal lymphoma.

This paper presented a retrospective review of medical records of HIV negative immunocompetent patients diagnosed with vitreoretinal lymphoma between 1994 and 2012. The aim of the paper was to evaluate the type and number of diagnostic interventions required to confirm...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....