You searched for "PPE"
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
1 October 2016
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Revealed: The growing crisis of workplace-related eye injuries
5 March 2025
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industry, NuVision, occupational health, occupational safety, eye health, patient information
Nearly half of UK workers believe their job puts their eye health at risk, yet are businesses overlooking this critical issue? New survey findings commissioned by NuVision Biotherapies highlight a rising yet often ignored concern in workplace health; eye injuries...
My COVID-19 songs
17 August 2020
| Anna Maino
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EYE - General
A portrait of Anna by Tamara Jovandic-Everson as part of #portraitsforNHSheroes. I am a consultant eye surgeon and these are my COVID songs. First of all, I have not even had time to digest the past six months, partly because...
Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD
1 December 2015
| Sofia Rokerya
|
EYE - Vitreo-Retinal
This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...
Ginko bilboa extract affects hypoxic retinal pigment epithelial cells
1 February 2014
| Khadijah Basheer
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EYE - Vitreo-Retinal
Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...
Retinoschisis
2 December 2019
| Sofia Rokerya
|
EYE - Vitreo-Retinal
In this retrospective study the authors evaluate the effect of pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling for lamellar macular hole (LMH) with or without macular retinoschisis in highly myopic eyes. Twenty-one highly myopic patients (22 eyes)...
Crystalline keratopathy in monoclonal gammopathy of undetermined significance
2 April 2025
| Kar Yen Phoong
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EYE - Cornea
Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...
Retinal ganglion cell loss in diabetes and diabetic retinopathy
1 October 2016
| Anjali Gupta
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EYE - Vitreo-Retinal
The aim of this observational case control study was to evaluate the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell loss. Cases were Chinese patients with type 2 diabetes with and without DR, aged 40-80 years. Eligible...
Air toxicity on retinal pigment epithelium
1 August 2015
| Khadijah Basheer
|
EYE - Vitreo-Retinal
This study investigated the potential toxic effects of air on primary human retinal pigment epithelial (RPE) cells in vitro. Clinically during pars plana vitrectomy air is used as either a temporary tamponade during air-fluid exchange or mixed with gas to...
Electrocautery and implantable cardiac devices
This is a literature review of the risks associated with bipolar and monopolar electrocautery in patients with a permanent pacemaker (PPM) or implantable cardioverter defibrillator (ICD). The authors found 12 publications which met their inclusion criteria, but within these there...
Is serum ACE useful in diagnosing sarcoidosis in uveitis patients?
1 February 2019
| Tasmin Berman
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EYE - Vitreo-Retinal
This retrospective clinical notes review assesses whether serum angiotensin converting enzyme (ACE) is useful in the diagnosis of sarcoidosis in patients presenting with uveitis. There were 1035 consecutive subjects presenting with uveitis as part of baseline investigations had a serum...
Infliximab in treatment of PVR
28 February 2025
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...
