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Genetic profiling for personalised healthcare solutions in AMD – an update
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...Large-scale study uncovers demographic and sex factors behind genetic cause of age-related visual loss
A new study has identified a major genetic contributor to Fuchs’ Endothelial Corneal Dystrophy (FECD), a common cause of vision loss, also highlighting the significant roles of sex and ancestry. FECD is a common, inherited eye condition that primarily affects...Worshipful Company of Spectacle Makers awards silver medal to Professor Robert Maclaren
At a Court Lunch held in the historic Apothecaries’ Hall last week, the Worshipful Company of Spectacle Makers awarded its prestigious Silver (Fincham) Medal to Professor Robert MacLaren. Professor MacLaren is Professor of Ophthalmology at the University of Oxford, Consultant...In conversation with Robert Henderson
Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
Age-related macular degeneration
This review article offers an up to date review of the genetic and environmental risk factors associated with aetiology surrounding age-related macular degeneration (AMD). The article briefly describes the typical clinical presentation relating to early and late stages of the...In conversation with Robert MacLaren at RCOphth 2019
In this video Professor Robert MacLaren talks to Eye News about the Keeler Lecture he gave on Gene Therapy for Retinitis Pigmentosa. Click the image below to see his answers to our questions.3rd Ophthalmic Drug Delivery Summit
Translating Long Lasting Efficacy & Less Invasive Retinal Drug Delivery The importance of matching the right drug delivery route to the right ophthalmic disease is more pressing than ever. The 3rd Ophthalmic Drug Delivery Summit is the premier gathering for...Corneal dystrophies simplified
Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...
