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214 results found

Intravitreal aflibercept for diabetic macular oedema

The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...

Lester Jones tubes: Can these be tolerated long-term?

The authors present a retrospective case review study of a cohort of patients with Lester Jones’ tubes first placed between 1969 and 1989, and who were reviewed within the last 15 years. Twenty-nine patients (33 eyes) were included in the...

Polymerase chain reaction evaluation of infectious multifocal serpiginoid choroiditis

This paper presents a retrospective review of infectious agents associated with multifocal serpiginous choroiditis (MSC) based on polymerase chain reaction (PCR) evaluation and specific antimicrobial therapy. The study included 13 patients with MSC who were evaluated with PCR for the...

Effect of voriconazole of vision of healthy volunteers

Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...

Modern trabeculectomy outcomes

This audit was conducted by the Trabeculectomy Outcomes Group Audit Study Group to report on the efficacy and safety of current trabeculectomy surgery in the UK. This is relevant in light of the fact that the trabeculectomy outcomes presented by...

Pars plana vitrectomy for vitreomacular traction syndrome

This paper presents a meta-analysis and systematic review of the safety and efficacy of vitrectomy for vitreomacular traction (VMT), based on 21 eligible articles from 460 identified. A strength of this study is that it provided pooled analysis across a...

Microbiology, risk factors and outcomes of microbial keratitis in Sydney, Australia

The authors present a retrospective case series including all patients with microbial keratitis and ocular surface diseases (OSD), including dry eye, blepharitis, Stevens-Johnson syndrome and / or ocular cicatricial pemphigoid, over a five-year period between 2012 and 2016. A total...

Orbital cavernous haemangiomas

This is a review of orbital cavernous haemangiomas (orbital cavernous venous malformations) managed over a 12-year period at a tertiary referral centre. Painless proptosis was the commonest presentation. One hundred and sixty-four patients (96 female and 68 male) underwent surgery...

Carcinoid tumours

This is a retrospective review of 28 patients with carcinoid tumours affecting the orbit. The mean age at presentation of the orbital involvement was 62 years, with a slight female preponderance, and 21% had carcinoid syndrome. Proptosis and diplopia were...

Practice patterns in managing exogenous endophthalmitis

The authors of this study conducted a global survey of medical institutions regarding management of exogenous endophthalmitis to assess current practice patterns for this sight-threatening emergency. Thirty-six (of 42 institutions) responded and were included in the analysis. Results were as...

Apr/May 2015 Quiz

History A 60-year-old man presented to the ophthalmologists with painful blurred left vision. Examination revealed a white vascular mass, occupying 60% of the anterior chamber space, arising from the iris. After conservative therapy, no useful vision remained. The eye was...

A standardised strategy for uveitis etiological diagnosis

This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...