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The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
A relationship between central serous retinopathy and obstructive sleep apnoea
This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....
Review of bupivacaine use in treatment of strabismus
This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...
Surgical correction of lacrimal gland prolapse
This is a systematic review of published literature on the management of lacrimal gland prolapse or ptosis. The authors found 16 publications which contained a description of any surgical correction of a prolapsed lacrimal gland, comprising seven case reports, four...
Diagnosis and management of paediatric keratoconus
This article reviews the current literature on paediatric keratoconus diagnosis and management. Paediatric cases pose challenges as they may not vocalise unilateral changes, difficulty in obtaining reliable imaging, faster rates of progression, difficultly with contact lenses and presumed worse outcomes...
Burden of caregiving for children with eye diseases
This review was conducted to examine the existent literature and characterise the psychological impact of caregiving for children with various eye diseases. The factors associated with the burden of caregiving were discussed in the context of each eye disease identified....
Strabismus prevalence in a Pakistan population
The aim of this study was to compile the available literature reporting the prevalence of strabismus in Pakistan and calculate the pooled prevalence of strabismus in the Pakistan population. Meta analysis was conducted with 10 studies with a total of...
