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PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
Laser speckle contrast imaging (LSCI) enables perfusion monitoring of the anterior segment during strabismus surgery: a study on the horizontal rectus muscles
Forty-four eyes with horizontal strabismus surgery involving medial and / or lateral rectus muscle detachment were recruited. The perfusion in the adjacent paralimbal and iris tissue was monitored with LSCI technique, by using a PeriCam PSI NR System. An infrared...
Optical coherence tomography angiography usability in measuring iris vasculature in strabismus surgery
The purpose of this study was to investigate the use of optical coherence tomography angiography (OCTA) as a screening tool for anterior segment ischemia (ASI) in strabismus surgery. Optical coherence tomography angiography measurements were taken in 18 subjects. Twelve were...
Cadaveric measurements of the Spiral of Tillaux
The authors conducted a cadaveric study to investigate and analyse the variability of the mean distances of the extra-ocular muscle insertion sites from the limbus as well as corneal diameters. The study included measurements taken from 30 white cavaders; 50%...
Quality and readability of online web information for childhood glaucoma
In this study, the quality, reliability, technical quality and readability of online information related to childhood glaucoma was assessed. This was a cross-sectional study of websites discussing childhood glaucoma. The authors undertook an analysis of 500 websites over a six-month...
Incidental ocular surface squamous neoplasia in pterygia: a systematic review and meta-analysis
This is a systematic review of 12 papers, which included 8688 participants and identified 202 cases of incidental ocular surface squamous neoplasia (OSSN) (pooled prevalence=1.32%, 95% confidence interval (CI), I2=95.3%). Meta-regression showed that lower OSSN prevalence was associated with greater...
Intravitreal ranibizumab for the treatment of myopic CNV
The authors conducted a prospective study. Sixty-four patients (65 eyes) attended the 12-month follow-up examination. The mean patient age was 47.8 years. Fifty-five patients (86.0%) were females. All patients had pathologic myopia (a spherical equivalent of more than − 6.0...
Under pressure: intraocular pressure and bariatric surgery
Obesity in the general patient population is increasing. The National Institute for Health and Care Excellence recommends bariatric surgery with body-mass index (BMI) of over 40, or between 35-40 and other significant disease that could be improved with weight loss....A career in uveitis
As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...Orbis teams up with the Alcon Foundation and OMEGA to improve eyecare in Zambia
The Orbis Flying Eye Hospital returns to Zambia for a three-week training project in Lusaka coinciding with World Sight Day on October 12.
