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My Top Five: Promising gene therapies for ocular conditions
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...My Top Five: Promising gene therapies for ocular conditions
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...
Cytokine levels in vitreous fluid in patients with pathological myopia
Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...
How does low-concentration atropine reduce progression of myopia?
This is a double-blind, randomised, placebo-controlled trial evaluating the effects of low-concentration atropine (0.05%, 0.025%, 0.01%) on ocular biometrics of myopic children. The aim is to determine what aspect of ocular biometrics low-concentration atropine influenced in reducing the progression of...Paediatric spectacle dispensing: more than a frame and lenses
It’s incredibly rewarding to fit a child’s first pair of spectacles and see their face light up; looking around to see the wider world for the first time. Sometimes it is so obvious that even the most reluctant parent will...An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...Game show freak
As a child of the 70s and 80s, there were limited television viewing opportunities. For the duration of the 70s there were only three channels, only moving to four with the launch of Channel 4 in 1982. Not only that,...A semi-automated algorithm for identifying glaucoma patients with blindness
Patients with sight impairment (previously referred to as partial sightedness) or severe sight impairment (previously referred to as blindness) are eligible for a certificate of visual impairment (CVI). Certification confers eligibility for a wide range of benefits administered by local...
Ectopia lentis management
This review discusses the management of non-traumatic ectopia lentis in the paediatric population focussing on the variety of surgical options for these patients. The review considers visual sequelae and conservative management, limitations for surgery with respect to historical and current...
