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Experimental Eye Research cover image.

ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

1 June 2018 | | EYE - Vitreo-Retinal
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Experimental Eye Research cover image.

MicroRNA inhibits corneal neovascularisation

1 August 2018 | | EYE - Cornea, EYE - General | Biomechanical stress, Corneal epithelium, MicroRNA-204, Neovascularization, VEGF, VEGFR2
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

1 April 2014 | | EYE - General
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
Progress in Retinal and Eye Research journal cover image.

A pulsatile pump in the TM, a new concept in trabecular outflow research

1 October 2021 | | EYE - Glaucoma | Aqueous outflow pump, Elastance, Glaucoma, Intraocular pressure regulation, Pulsatile aqueous outflow, Schlemm's canal valves
This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...
Journal of Neuro-Ophthalmology cover image.

Predicting ischemic lesion location using perimetry

3 August 2023 | | EYE - Neuro-ophthalmology
The authors present a retrospective records review, using the search terms homonymous hemianopia, visual field loss and MRI. Only posterior circulation artery territory ischemic strokes were included. Demographics, stroke details and initial and follow-up with 24-2 SITA Standard perimetry results...

Optimising the ocular surface by managing meibomian gland dysfunction

1 February 2016 | | EYE - Cornea
Meibomian gland dysfunction (MGD) is ubiquitous. Ocular surface inflammation and irritation are prevalent in most ophthalmology clinics: corneal, cataract, glaucoma, oculoplastic, paediatric, vitreo-retinal, medical retina and refractive surgery. These patients also represent roughly one third of those attending for emergency...

Worshipful Company of Spectacle Makers awards silver medal to Professor Robert Maclaren

1 April 2025 | WCSM, Awards, opthalmology, Contributions, vision research
At a Court Lunch held in the historic Apothecaries’ Hall last week, the Worshipful Company of Spectacle Makers awarded its prestigious Silver (Fincham) Medal to Professor Robert MacLaren. Professor MacLaren is Professor of Ophthalmology at the University of Oxford, Consultant...

A new observation point: updating the nomenclature and classification with OCT

3 June 2021 | | EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...

Portable corneal topography – exploration of a prototype

1 June 2022 | | EYE - Imaging, EYE - General
Ophthalmic imaging devices, such as corneal topographers, are not widespread in the developing world. A small device that connects to a smartphone might be a solution to improve developing nation access to corneal imaging. I recently had the opportunity to...

Moorfields: Paediatric eye emergencies for the non-paediatric ophthalmologist

26 November 2025
Clinicians who primarily work with adults, often lack confidence when it comes to assessing and managing emergency eye problems in children. This half-day course aims to address that gap by providing practical, accessible education in paediatric ophthalmology for non-paediatric ophthalmologists.

The results of the last survey Dec20

7 December 2020 | | EYE - Cataract, EYE - Refractive, EYE - General
The responses to the first question in this survey demonstrate the need for it and the significant variation in practice we see in even relatively simple management decisions. Patients are seen regularly with occludable drainage angles and listed for YAG...

Capacity-strengthening for diabetic retinopathy services in low- and middle-income countries

3 February 2023 | | EYE - General
Introduction DR-NET eye health professionals in low- and middle-income countries (LMICs) have, since 2015, been able to access training in diabetic retinopathy (DR) grading provided by Gloucestershire Retinal Education Group (GREG). GREG, led by Professor Peter Scanlon and based at...