You searched for "pigment"

3088 results found

Reproductive counselling for females with X-linked inherited retinal diseases

The authors report a survey-based study of 118 female patients who were genetically confirmed carriers or obligate carriers of an X-linked inherited retinal disease. The majority (66.9%) of these patients were carriers of choroideremia; other diagnoses included retinitis pigmentosa, X-linked...

Life’s rich tapestry

Have you ever watched someone cross-stitch, or do needle-point? I recently had the joy of observing my teenage daughter create such an artwork. She separated all the threads into the various colours, and then started to follow the instructions carefully....

Life in the glaucoma laboratory

When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...

Is it NAION… Now what?

Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

An unusual case of silicone oil in the anterior chamber simulating intraocular implant

Silicone oil internal tamponade has been used for over 50 years, even prior to pars plana vitrectomy [1].Over a course of time silicone oil may migrate to the anterior chamber through the pupil. This may disperse in the form of...

Periorbital and subconjunctival emphysema - a sign of orbital rim fracture

Background Orbital emphysema is a condition where air is present in orbit or periorbital tissues [1]. It is most commonly caused by trauma leading to orbit fracture, where air from paranasal sinuses is allowed to enter the orbit. The most...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

The David J Apple International Laboratory for Ocular Pathology – a legacy of pioneering IOL research

David Apple and Gerd Auffarth. The Apple Lab at the David J Apple Center for Vision Research in Heidelberg is a thriving international laboratory for research into intraocular devices. The lab continues the work of David J Apple, a world-renowned...

What's trending Apr/May 2024

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #GrahamNorton #eyelids Graham Norton’s chat show is always a must-watch in my book. I was particularly surprised to find two eye-related...

Phaco nightmares

I am interested in the stressful nature of cataract surgery from the surgeon rather than the patient’s perspective. It is an issue that has quite literally kept me awake at night. Part of getting to grips with a problem is...

Lockdown and eye health – a case of accommodative spasm

A 25-year-old male presented to the eye casualty with a one-day history of sudden onset worsening vision. More specifically, he noted his vision was more blurred than usual and this was more exaggerated for near-work than for distance-work. He was...