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Efficacy of combined vitrectomy with intravitreal corticosteroid injection for ERM

In this study the authors evaluated the efficacy of vitrectomy combined with corticosteroid injection for idiopathic epiretinal membrane (ERM). A systematic literature review was conducted by searching three electronic databases, PubMed, Embase and Medline, up to 2020 for relevant studies....

What can artificial intelligence do to improve sustainability in the delivery of ophthalmic care?

The 2025 NHS 10-year plan, titled ‘Fit for the Future’, emphasises a significant shift from analogue to digital, with a strong focus on integrating AI and other technologies to transform healthcare. The plan aims to make the NHS the "most...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

A window to 2024 and beyond?

The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...

AI detects eye changes that lead to sight loss in young people

Use of Artificial Intelligence (AI) can accurately predict when young people with the sight- threatening eye condition kerataconus need treatment to stabilise the cornea and prevent loss of vision. Developed by researchers at Moorfields Eye Hospital and UCL Institute of...

Conference Report: RCOphth 2025

This year’s Royal College of Ophthalmologists Annual Congress in Liverpool brought together eyecare professionals from across the country and beyond for four days of thought-provoking content, collaborative discussion and exciting glimpses into the future of ophthalmology. The opening day was...

Navigating challenges and embracing growth

Embarking on a career in ophthalmology is both exhilarating and challenging. Moving through the various stages of training, from foundation years to specialty training, brings a steep learning curve and intense demands, often necessitating significant adaptations in both professional and...

My Top Five: Visionary inventions in ophthalmology

When we see how technologically forward and advanced modern-day medicine is, we forget that it is also an age-old, ancient profession with a rich, intriguing history that we remain unaware of. Ophthalmology in particular has always been at the forefront...

Cell injection therapy for endothelial failure

This is a prospective observational study involving 11 eyes of 11 patients with pseudophakic endothelial failure who underwent human corneal endothelial cell culture (hCEC) injection therapy for endothelial failure. This study aimed to evaluate the long-term five-year postoperative data for...

BT outcomes under open versus closed sky technique

This retrospective study compared open versus closed sky BT injection techniques without electromyography (EMG) control in 135 patients (31 open sky and 104 closed). Patients were aged 1-50 years for open sky and 2-34 years for closed. There was a...

Review of bupivacaine use in treatment of strabismus

This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...