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Orbital cellulitis in Scotland: current incidents, aetiology, management and outcomes

This is a one year prospective study using the Scottish ophthalmic surveillance unit reporting system amongst Scottish ophthalmologists. Only patients residing within Scotland with a new diagnosis of orbital cellulitis between November 2011 and October 2012 were including in this...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Cell injection therapy for endothelial failure

This is a prospective observational study involving 11 eyes of 11 patients with pseudophakic endothelial failure who underwent human corneal endothelial cell culture (hCEC) injection therapy for endothelial failure. This study aimed to evaluate the long-term five-year postoperative data for...

BT outcomes under open versus closed sky technique

This retrospective study compared open versus closed sky BT injection techniques without electromyography (EMG) control in 135 patients (31 open sky and 104 closed). Patients were aged 1-50 years for open sky and 2-34 years for closed. There was a...

Review of bupivacaine use in treatment of strabismus

This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...

BTA injection to treat convergence insufficiency

The outcomes of patients with convergence insufficiency (CI) treatment with botulinum toxin A (BTA) in one or both lateral rectus muscles are reported. This was a retrospective study of 23 patients; eight males, 15 female, mean age 59 years (range...

BT vs primary surgery for infantile esotropia

In this study, the success rate of treatment for infantile esotropia (IET) patients who had surgery because of under correction after botulinum toxin (BT) is compared to those having primary surgery. The study included 52 patients (27 male) with mean...

Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...