You searched for "longitudinal"

171 results found

Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?

The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...

What are the features of facial nerve palsies in children?

The aim if this study was to report ophthalmic related findings and complications in children with facial palsy. Medical records from a tertiary centre were retrospectively searched for children 16 years and under with a diagnosis of facial palsy, over...

Saccades and contrast sensitivity in retinoblastoma survivors

The authors report a cross-sectional study, which recruited children aged 5 to 18 years old who completed treatment completion for retinoblastoma more than six months ago. Exclusion criteria included bilateral enucleation and pre-existing conditions associated with cognitive impairment. A total...

Comparing retinal thickness in Parkinson’s disease, essential tremor and healthy controls

This study aimed to compare retinal findings in chronic essential tremor (ET), early Parkinson’s disease (PD) and healthy controls. Those recruited with ET had to have received a diagnosis a minimum of three years previous and those with PD had...

Changes, with increasing age of children, in optic nerve head parameters and retinal thickness

In this study, the authors aimed to compare stereometric parameters of the optic disc and inner retinal layer thickness (peripapillary retinal nerve fibre layer (pRNFL) and ganglion cell inner plexiform layer (GCIPL)) at two time points in the same children...

Photophobia associated with migraine: Investigating associations with productivity

The aim of this study was to investigate an association between severe photophobia linked to migraine and reduced work productivity. Cases were extracted from the American Registry for Migraine Research (ARMR) with the following criteria: diagnosed with migraine, data available...

Opening the AI ‘black box’ for glaucoma

Artificial intelligence (AI) models show great promise for glaucoma detection using retinal images, but their ‘black box’ nature is a major barrier to clinical adoption. Clinicians are often hesitant to trust a diagnosis without understanding its reasoning. This paper provides...

Identification of potential social determinants which may impact on idiopathic intracranial hypertension

The authors analysed cross-sectional data with the aim of exploring the social determinants of idiopathic intracranial hypertension (IIH). The data was obtained from the National Institute of Health (NIH) All of Us research programme (version 6 – May 2018 to...

Vision screening and socio-demographic disparities in Iranian school entrants

The authors present a large population-based cross-sectional study evaluating the vision status of children entering school in Iran and its association with socio-demographic characteristics. Parents reported whether their children had healthy vision, wore eyeglasses, or had suspected vision problems, alongside...

Literature review of associations for refractive error, and correction, on development of amblyopia and accommodative esotropia

The authors report a literature review to determine the available evidence for the association between hypermetropia, astigmatism, anisometropia and the influence of early glasses and the development of amblyopia or accommodative esotropia. Studies were included where children were first examined...

Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform

The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...

The structure function relationship in glaucoma

Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...