You searched for "macular"

2476 results found

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

Use of pattern-reversal VEP in congenital Zika syndrome (CZS) assessment

The authors conducted pattern reversal visual evoked potential (PRVEP) in children with congenital Zika syndrome (CZS) and report the correlates with visual acuity, fundus alterations and severity of microcephaly at birth. This was a cross-sectional study of 37 children with...

Progress for a more sustainable practice in ophthalmology

Climate change is widely considered to be the greatest threat to health in the 21st century and is accompanied by other environmental considerations such as air and water pollution that impact on human health [1,2]. These problems are, in no...

Coming to terms with AI

A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Choroidal and retinal vascular changes after horizontal rectus surgery

The authors used wide field swept-source OCT angiography (SSOCTA) to evaluate changes in retinal and choroidal blood flow before and after horizontal rectus muscle surgery. They aimed to characterise the haemodynamic impact of extraocular muscle surgery on the posterior pole...

Phacoemulsification Cataract Surgery

The book, through a ‘rear-ended’ approach to training, covers basic and fundamental skills for the novice ophthalmic surgeon embarking on phacoemulsification cataract surgery. As the preface states, this is a ‘key surgical technique for an ophthalmologist to learn’. However, achieving...

Aspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula

Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...

Bionic eyes: deciphering the neural circuitry of vision restoration

As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...

My ophthalmology taster week experience at Whipps Cross Eye Treatment Centre

Deciding to explore ophthalmology Having read about ophthalmology, I have always found myself fascinated about what a career in ophthalmology entails. I have often wondered what ophthalmologists actually do, as we as medical students did not have a lot of...

Can a monocular occlusion test for assessing divergence excess intermittent exotropia be accurate and quicker?

The authors investigated whether a 15-minute monocular occlusion test is as effective as the traditional 45-minute monocular occlusion test in assessing patients with divergence excess intermittent exotropia. The prospective, randomised observational study included 22 children aged 5–14 years. Children with...

Neurofibromatosis with multiple bilateral choroidal nevi and literature review

The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...