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Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...ARx - Augmented Reality Headset
In a continuing look at wearable technology, for those with sight impairment, for Aug/Sep we are looking at the recently released ARx. In previous issues we have covered the Envision Glasses and the OrCam MyEye. The ARx is a device...The most frequent complaints and claims in ophthalmology – a Medical Protection Society (MPS) analysis
The authors look at the reasons behind medico-legal cases reported to MPS and share key learning points. Complications following ophthalmology surgery are rare, however, medico-legal cases are not uncommon due to the significant impact they can have on patients’ lifestyles....Ophthalmology in the Middle East: Reflections from two electives in Jordan and the UAE
In the summer of 2021, I was fortunate enough to embark on two electives in ophthalmology at the Shami Eye Centre in Amman, Jordan, and Moorfields Eye Hospital in Dubai, United Arab Emirates (UAE). These eye hospitals serve distinct populations,...Ciclosporin and dry eye
Dry eye has an estimated prevalence of between 5 and 50% worldwide and has physical, psychological and socioeconomic consequences for the human population [1]. Loss of tear film homeostasis with associated ocular surface inflammation causes symptoms ranging from ‘tired’ eyes...An interview with a glaucoma consultant: Insights for aspiring trainees
In this article, Resident Doctor Chi Kit Yan sits down with Consultant Glaucoma Specialist Salman Sadiq and explores the daily life of a glaucoma specialist, the pros and cons of the role, how trainees can prepare for this subspecialty, and...Building research capacity through the VISION 2020 LINKS Programme
The aim is to build capacity for research in the region covered by the College of Ophthalmology of Eastern, Central and Southern Africa (COECSA). The project will build research capacity in three ophthalmology training institutions by ‘training the trainers’ and...The power of the full blood count
Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...Ocular bubbly: a vitreoretinal update on the art of gases
The authors remind us of the revolutionary impact gases have had on retinal surgery. In 1938, Rosengren attempted to improve his retina repair surgical outcomes [1]. He discovered that suturing the retina or pressing externally on the sclera were not...Best way to detect glaucoma progression: by reflecting on the past 25 years
Glaucoma – a condition of optic neuropathy leading to progressive visual field loss often associated with raised intraocular pressure. It is fair to say that our definition for this condition has remained unchanged over the last 25 years and the...Aspiration of anteriorly migrated dexamethasone implant using an 18G intravenous cannula
Intravitreal dexamethasone (Ozurdex 0.7mg) is a biodegradable, sustained-release implant used to manage diabetic macular oedema, macular oedema secondary to retinal vein occlusion, and non-infectious posterior uveitis due to its anti-inflammatory effects and VEGF suppression [1]. While effective, the implant may...
