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Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...Developments in retinal pigmentation measurement and the hopes of an equitable future
Our AI & Oculomics co-editor, Nima Ghadiri, sat down with Abraham Olvera-Barrios from Moorfields and Anand Rajesh from the University of Washington to discuss their recent international study into retinal pigmentation and its wider clinical, technological and academic applications. Can...
Minimally Invasive Glaucoma Surgery – A Practical Guide
The treatment of patients with mild to moderate glaucoma has evolved rapidly in the last decade. Traditionally, medical and laser treatments were the mainstay of therapy for this group of patients. Trabeculectomy, non-penetrating surgery and glaucoma drainage implants were reserved...Choroidal folds
Choroidal folds are undulations of the choroid, Bruch’s membrane and pigment epithelium, with wrinkling of the overlying retina. They may be idiopathic but can also be caused by a number of different conditions. Case report A 60-year-old male patient was...Urban Changes and Rural Struggles for Ophthalmology in China
China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...Informed consent in ophthalmology care in the UK: A critical component of patient‑centred practice
Informed consent is a cornerstone of ethical and legal practice in healthcare, particularly in fields like ophthalmology where specialised interventions can have significant implications for a patient’s vision and quality of life. In the UK, informed consent is not merely...Lord Trees and Baroness Sugg call to end Neglected Tropical Diseases with charity coalition at Westminster event
UK Coalition against Neglected Tropical Diseases works alongside co-host parliamentary reception in the House of Lords.
Rural amblyopia prevalence in Iran
The purpose of this study was to estimate the prevalence of amblyopia in subjects aged 3-93 years living in under-served rural areas of Iran. The study was conducted in 2015 in two under-served districts randomly selected from the southwest and...
Trabeculectomy ab interno (trabectome)
This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...
Rate and predisposing factors for post-vitrectomy cataract formation in children
This study was a retrospective analysis of post-vitrectomy cataract formation in the general paediatric population. The authors aimed to determine the number of phakic children needing cataract surgery after vitrectomy surgery and related perioperative factors. The study was a 10-year...
