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Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
Intraocular pressure reduction after cataract surgery
Several studies have shown the efficacy of cataract surgery in lowering intraocular pressure (IOP), especially in angle closure glaucoma compared to open angle. A total of 156 eyes of 109 patients (without glaucoma or with medically controlled glaucoma) were included....
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...Non-organic visual loss
Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...Ultrasound biomicroscopy (part 2): primary angle closure
Patients with primary angle closure or primary angle closure glaucoma [PAC(G)] comprise a significant subgroup affecting around 10% of glaucoma patients amongst Caucasians. Assessment of the patient with angle closure, or narrow angles, requires gonioscopy. However, whilst identifying the presence...Congenital cataract
Congenital cataract is the clouding or opacification of the lens that occurs at birth or weeks after (infantile cataract). They can be unilateral or bilateral and vary in form, size and location, and consequently the visual impact, management course and...Ambient scribes: The silent revolution
Clinical practice is in the midst of a profound digital transformation with a new wave of technology gaining increasing prominence: ambient scribes. These AI-powered tools streamline documentation by converting doctor–patient conversations into structured clinical notes in near real time. Healthcare...SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis
This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...An eyeful of independence
Scots will decide this September whether or not Scotland should be an independent sovereign state. “As all key areas of our business are already fully devolved, it’s very much business as usual for us,” noted a spokesperson for Healthcare Improvement...UKPGS (UK Paediatric Glaucoma Society) Meeting 2023
by SP Gurney The UK Paediatric Glaucoma Society (UKPGS) 2023 annual meeting took place on 27 January at the Cavendish Conference Centre in London. Professor Sir Peng Khaw, UKPGS President, welcomed nearly 100 delegates from around the world, with representation...
Tumour characteristics influencing visual field outcomes
This retrospective study aimed to explore correlations between pituitary tumour characteristics which influenced visual field changes. Cases of transsphenoidal surgery from a six-year period resulting in a pathologic diagnosis of pituitary adenoma from a single centre were identified. Individuals were...
