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RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Genetic analysis of choroideremia families
Choroideremia (CHM) is a rare X linked recessive chorioretinal dystrophy. Symptoms include nyctalopia and progressive peripheral field loss. Female carriers may have mild symptoms. Choroideremia is known to be caused by a mutation in the CHM gene. A multicentre human...
Postural control in glaucoma patients with virtual reality
The authors report on a cross-sectional study evaluating postural control and history of falls in glaucoma patients. History of falls was obtained using the Falls Screening and Referral Algorithm. Postural stability was assessed using a force platform under four conditions:...
Vital dyes in ophthalmology
This comprehensive review gives an excellent summary of the uses and properties of the different dyes available to aid better visualisation and diagnoses in ophthalmology. The authors clearly display the pharmacological properties, molecular details, osmolarity and indications in clinical ophthalmology...
Congenital aniridia with or without retinal detachment
The authors present the clinical and molecular genetic evaluations performed on a large Iranian pedigree with 26 aniridia affected patients in four generations and some with retinal detachment. Members of the family affected with aniridia were invited to participate after...
Myopia rate of change from 5-20 years
Data was collected from the 2008-12 KNHANES survey and the study included 7695 of 9351 subjects with refractive data. The mean age was 11.8 years (5-20 range) with 48.2% female. Mean spherical equivalent was -1.82 ±2.23D. For five-year-olds, the mean...
Transconjunctival eyelid weight insertion
This is a description of a new surgical technique to insert upper lid weights via a posterior, transconjunctival route. Following local anaesthetic, the upper lid was everted over a Desmarres retractor with a silk traction suture. A 5mm high central...
BESTi: a new index to detect subclinical keratoconus
In this multicentre, case-control study, the authors develop a new index, named Boosted Ectasia Susceptibility Tomography Index (BESTi), to detect early cases of keratoconus. This index was derived from multiple logistic regression analysis of 22 variables of tomography scans. The...
Modified technique in place of ultrasound biomicroscopy
The authors describe a modified immersion B-scan ultrasonography that includes a standard B scan probe of 10MHz, a surgical glove and sterile saline to fill a finger of the surgical glove – tied off to create the desired immersion standoff...
New management algorithm for acute post cataract endophthalmitis
In this study, the authors aimed to establish an objective algorithm for recommending urgent pars plana vitrectomy (PPV) to help improve visual outcomes in the current era of clear corneal-incision phacoemulsification and small gauge PPV. This study examined 150 cases...
Autologous scleral button for anterior defect in evisceration surgery
This is a small case series of five patients who have had evisceration surgery using a new technique. The anterior defect created when removing the corneal button has been closed by taking an autologous posterior scleral graft inferomedial to the...
