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877 results found

Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant

This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...

Alternative diagnosis in cases of poor response to amblyopia therapy

The aim of this study was to assess the prevalence of coexistent ocular pathology and identify / describe the factors that contribute to undiagnosed alternate diagnosis and / or co-existent pathology at initial presentation in patients referred as potentially amblyopic....

Vascular density evaluated by SS-OCTA and microperimetry in RP

The aim of this retrospective, observational cross-sectional one-year study was to evaluate the retinal and choroidal vessel density in the macular area with swept-source optical coherence tomography angiography (SS-OCTA) in patients of retinitis pigmentosa (RP), to compare this data with...

Results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions

This retrospective, observational multicentre study investigated the anatomic and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes. Data was collected...

Outcomes in intermediate age-related macular degeneration (AMD): A MACUSTAR study report

Intermediate AMD (iAMD) is the most high-risk AMD stage for progressing to late AMD. This article gives the report of the MACUSTAR study. A wide range of assessments were conducted across 20 sites in seven European countries, in accordance with...

Everyday diabetes medicine could treat common cause of blindness

Doctors have found that metformin, an everyday medicine for diabetes, is associated with less progression of age-related macular degeneration (AMD), the commonest cause of blindness in western countries. People with diabetes over the age of 55 years taking metformin were...

Comparison of the efficacy of anti-VEGFs agents in nvAMD

This retrospective multicentric study conducted in Israel and Canada, compared the efficacy of bevacizumab, aflibercept 2mg and ranibizumab as first-line treatments for neovascular age-related macular degeneration (nvAMD). Included were treatment-naïve nvAMD eyes receiving ≥12 months of treat-and-extend (T&E) anti-VEGF therapy...

Cambridge Ophthalmological Symposium 2024: Evolution and the Eye

by Anushka Irodi, Y5 Medical Student, University of Cambridge, UK. The 52nd Cambridge Ophthalmological Symposium, a renowned two-day national meeting, took place on September 5th and 6th, 2024 at St John’s College, Cambridge, UK. It brought together international leading minds...

Two-year GATHER2 data: anatomical gains, functional questions for avacincaptad pegol in geographic atrophy

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) remains a leading cause of irreversible central vision loss, and complement dysregulation has long been implicated in its pathogenesis. In 2023, the US FDA approved the first two GA therapies, both...

Cutting-edge practice in glaucoma care: what, how and why?

More effective treatments and drug delivery modalities, implantable minimally invasive glaucoma surgical (MIGS) devices, as well as accelerating clinical research programmes, will transform the surgical and clinical management of glaucoma in the near future. There is also an ever-greater emphasis...

Strategies for managing neovascular AMD and DMO in routine clinical care

Treatment practice in the management of neovascular age-related macular degeneration (AMD) and diabetic macular oedema (DMO) illustrate increasing adoption of patient-tailored treatment approaches based on initial diagnosis and regular monitoring of imaging and visual outcomes in routine clinical care. The...

Advances and developments in medical retina

The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...