You searched for "Simulation"
MPH treatment effect in ADHD on choroidal vascular index
In this study the authors aimed to investigate the choroidal vascular index (CVI) in treatment-free children with ADHD, children regularly taking methylphenidate (MPH) and healthy controls. This was a prospective cross-sectional study of 52 patients with newly diagnosed ADHD, 46...Choroidal thickness in ocular sarcoidosis by OCT measurement
1 December 2014
| Nikolaos D Georgakarakos
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EYE - Vitreo-Retinal
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...
Effects of blood donation on the physiology of the eye
1 December 2018
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
ROP anti-VEGF treatment review
The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments
1 February 2017
| Manoj V Parulekar
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EYE - Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...
Progression of macular atrophy on long-term anti-VEGF therapy for AMD
3 October 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Anti-VEGF therapy, Long term, Macular atrophy, neovascular age-related macular degeneration
This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...
Autophagy in lens mitochondria loss
1 April 2014
| Graham Wallace
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EYE - Cataract, EYE - Refractive
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ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
Thyroid eye disease
Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....Eyes on Tomorrow podcast: “Desert Island Discs for ophthalmologists”
What happens when an ophthalmologist and optometrist get chatting in a pub, over a couple of pints of Guinness, about how they could create something educational and entertaining for ophthalmologists and optometrists? The answer is the Eyes on Tomorrow podcast....Blurred vision post liver transplant: to blame the house cat or not?
1 October 2014
| Stephenie Tiew, Gideon Hirschfield, Ian Pearce, Nicholas Beare
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EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Strabismus, EYE - Refractive, EYE - Vitreo-Retinal
This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...
Cementing a VISION 2020 LINK partnership between Blantyre and Liverpool – building capacity for DR services alongside research
1 August 2016
| Petros Kayange, Gerald Msukwa, Michael Briggs, Marcia Zondervan, Nicholas Beare
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EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Malawi is a small land-locked country in eastern Africa with a growing population of over 17 million people. About 45% of the population is aged 14 or under; only 5% are aged 60 or over. The gross national income per...
Inferior oblique adherence syndrome
5 June 2020
| Fiona Rowe (Prof)
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EYE - Paediatrics, EYE - Strabismus
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Inferior oblique anteriorization, hypotropia, inferior oblique adherence, limitation of levoelevation
A case is reported of a 14-year-old with inferior oblique muscle adherence and fat adherence following unilateral inferior oblique (IO) anteriorisation. Following surgery, the patient developed consecutive esotropia, ptosis and marked limitation of laevoelevation. Forced duction test was positive for...

