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Emerging developments in dry eye
An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...
Surgical oculocardiac reflex
The authors evaluated the incidence of oculocardiac reflex (OCR) during strabismus surgery to determine its associated risk factors at a tertiary referral centre. Seventy-six patients were reviewed; 51.3% male and a mean age of 15±12 years. Strabismus surgery was bilateral...
Marcus Gunn jaw winking without ptosis
This is a review of 72 cases of Marcus-Gunn jaw winking syndrome. The authors reviewed all their congenital ptoses seen over a 16 year period and found 72 Marcus-Gunn cases of out of a total of 848 patients. Within the...
MR- vs. LR+ for divergence insufficiency
A retrospective study was conducted to compare the efficacy of medial rectus recession and lateral rectus resection as surgical interventions for divergence insufficiency in 18 patients. These were cases of non-neurological cause. Two patients in each group required postoperative adjustment....
An unusual case report of bilateral abducens paralysis
In this case report a nine-year-old girl develops bilateral abducens nerve paralysis, caused by vertebrobasilar dolichoectasia. Vertebrobasilar dolichoectasia is characterised by dilation, tortuosity and marked elongation of the vertebral and basilar arteries. Clinical findings result from the compression and displacement...
Sagging eye syndrome surgery
This retrospective study evaluated outcomes of surgery for patients with sagging eye syndrome (SES) from 1994 to 2014, to determine recurrence rates of strabismus. The study identified 103 cases; 93 requiring surgery for symptomatic small angle strabismus and 10 requiring...
Management of restrictive diplopia after ptergium surgery
This single centre retrospective case series included 15 patients with restrictive diplopia after ptergium excision. The mean time from surgery to diplopia was six months and all patients had a moderate limitation of abduction in the operated eye causing an...
Using fusion measures to guide strabismus surgery
In this study the authors targeted patients with non-accommodative decompensating distance esotropia with investigation of prior binocular single vision. Choice of target angle was based on the individual’s fusional amplitudes. The target angle aimed to be less than the distance...
