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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Post-stroke visual impairment: how big is the problem, how do we identify it, what we can do about it, and why does it matter?

In the UK, 100,000 new strokes occur each year, with 1.3 million stroke survivors [1]. This article will focus on post-stroke visual impairment, discussing topics of how common it is, how it can be detected, possible management options and how...

The happiness coefficient: Pete’s hidden curriculum Part 5

Jeremy: Come on, man, shake your booty! Tonight even Paxman’s out, hoovering up lines of crank off Krishnan Guru-Murthy. Tonight’s the big one.Mark: Jeremy, all rational people agree it’s a truth self-evident that it’s impossible to have a good time...

The Rapid Assessment of Avoidable Blindness: How ICEH maintains the cornerstone of global eye health data

In this paper we will discuss The Rapid Assessment of Avoidable Blindness (RAAB), a survey methodology that has become the single largest source of population eye health data globally. The origins of RAAB The RAAB is a rapid, population-based survey...

Eye

Blinking blepharitis has a lot to answer for…

Never ignore the small things’…someone once said. There is no doubt blepharitis is one of the most common eye conditions encountered daily, but with the typical pressures of a busy outpatient department, the management of more obvious, sight-threatening conditions necessarily...

House of cards

When I was a junior doctor in the late 1990s writing my first scientific papers, once each article was finished, I had to fill out an application form, print out multiple copies and then walk to the post office at...

Rare presentation of giant cell arteritis in Chinese subjects

Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...

Lord Trees and Baroness Sugg call to end Neglected Tropical Diseases with charity coalition at Westminster event

UK Coalition against Neglected Tropical Diseases works alongside co-host parliamentary reception in the House of Lords.

Thyroid eye disease

Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....

Sexually transmitted conjunctivitis – the REALLY sticky eye

Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...

Acute dacryoadenitis secondary to COVID-19

Acute dacryoadenitis is defined as the rapid onset of discomfort and swelling of the lacrimal gland, classically giving rise to an S-shaped ptosis [1]. Dacryoadenitis is the most common cause of a painful mass in the lacrimal gland in young...