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Seminars in Ophthalmology journal front cover image.

Leber’s hereditary optic neuropathy: from lab to clinic

1 October 2016 | | EYE - Neuro-ophthalmology | Hereditary optic neuropathy, Leber hereditary optic neuropathy, mitochondrial optic neuropathy, optic neuropathy
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...

Illuminating task lighting

1 October 2019 | | EYE - General
Good lighting is always important but especially for patients who are visually impaired. Janet Pooley provides an overview. We tend to discuss lighting with patients when their vision is reduced, and where we are considering higher reading adds or low...

Ocular bubbly: a vitreoretinal update on the art of gases

5 April 2022 | | EYE - Vitreo-Retinal, EYE - General
The authors remind us of the revolutionary impact gases have had on retinal surgery. In 1938, Rosengren attempted to improve his retina repair surgical outcomes [1]. He discovered that suturing the retina or pressing externally on the sclera were not...

The structure function relationship in glaucoma

1 April 2017 | | EYE - Glaucoma
Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Your 101 guide to interpreting the Pentacam®

3 June 2026 | | EYE - Imaging, EYE - Cornea
Anterior segment tomography produces a three-dimensional assessment of anterior and posterior corneal structures. The Pentacam uses rotating Scheimpflug imaging to generate cross-sectional scans of the cornea and anterior chamber, essential for detecting ectasia, refractive surgery screening and longitudinal monitoring. However,...

Ophthalmic viscoelastic devices: Useful insights for a novice cataract surgeon

4 February 2025 | | EYE - Cataract
Ophthalmic viscoelastic devices (OVDs) are essential in many different stages of cataract surgery. This article discusses the categories of OVDs and their respective properties, and highlights their uses in different scenarios faced in cataract surgery. Ophthalmic viscoelastic devices are gel-like...

Capacity building for ophthalmic nursing in Ghana, Botswana and Tanzania

2 December 2019 | | EYE - General
Ophthalmic nurses (ON) have been the backbone of eye health services in Africa since the mid-20th century and remain the largest single cadre of allied ophthalmic personnel in Commonwealth countries in Africa. Numbers are currently estimated at between 3500 and...

The treachery of images – making sense of OCT imaging

1 June 2016 | | EYE - Vitreo-Retinal, EYE - Imaging
In 1929 Belgian surrealist Rene Magritte produced his painting La Trahison des Images. It depicted an old fashioned pipe for smoking tobacco and underneath were the words “ceci n’est pas une pipe”, this is not a pipe. You may wonder...

A rare case of endogenous panophthalmitis: Nidus from an E. coli urinary tract infection

3 June 2026 | | EYE - Imaging, EYE - Orbit, EYE - Pathology
Endogenous bacterial endophthalmitis (EBE) is a form of severe inflammation caused by haematogenous spread of a virulent bacterium from a nidus elsewhere in the body to intraocular tissues. It is a rare occurrence and only constitutes around 2–8% of all...

AI & Oculomics: a new section for Eye News

2 February 2024 | | EYE - General
Inaugurating this new regular section on the exciting landscape of AI and oculomics, we provide an overview which delves into the historical context and the etymology of this field, reviews the current state of play and contemplates possibilities and hopes...

Virtual reality for the ophthalmic trainee

1 June 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
If you believe the tech blogs 2015 is the year of virtual reality. Industry experts believe this will be due to the potential commercial release of the poster boy of this new revolution, the Oculus Rift. This is a headset...

A career in uveitis

7 December 2020 | | EYE - Vitreo-Retinal, EYE - General
As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...