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Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Video Atlas of Oculofacial Plastic and Reconstructive Surgery

The second edition Video Atlas of Oculofacial Plastic and Reconstructive Surgery by Korn and Kikkawa provides an overview of traditional and contemporary reconstructive and cosmetic eyelid, lacrimal and orbital surgical procedures. The book includes of 1600 intraoperative illustrations, in addition...

Lateral tarsal strip versus Bick’s procedure in correction of eyelid malposition

The authors report a retrospective case series of patients, to evaluate the effectiveness of Lateral Tarsal Strip (LTS) and Bick’s procedure (lateral wedge resection) for all types of involutional lower eyelid malposition, at two centres between January 2012 and 2015....

The paediatric cataract: an overview of the diagnosis and management

In this second article (see first article here), Samuel Aryee and Rhys Dumont Jones review the challenges involved in managing this condition. Examination and diagnosis Cataracts in children can appear in a variety of forms, each presenting in a different...

Surgical correction of involutional lower lid entropion

This is a retrospective comparative study. The authors analyse results of 281 eyelids with involutional entropion operated by two surgeons, 89 treated with buried resorbable imbricating sutures and 192 with non-buried non-resorbable sutures. The horizontal lid laxity was corrected by...

Cataract surgery in the extremely small eye: morphology, comorbidities and outcomes in 300 eyes

This is a retrospective study from Heidelberg University, Germany, between January 2009 to October 2023, including 300 eyes of 191 patients undergoing cataract surgery with short axial length requiring lens implantation of > 30 dioptres. Eyes were classified into the...

Piloting myopic control glasses effects on axial length under mesopic conditions

This study aimed to pilot whether axial length reduces when being treated with myopia control glasses in mesopic conditions. Participants were required to have single-vision glasses with spherical equivalent between -1.00 and -5.00 dioptres, astigmatism less than -1.00 dioptre, a...

The results of the last survey Apr24

It has been a few years now since we started these surveys and I continue to be amazed by the variance in our practice. As a patient, I think I would expect there to be more consistency and evidence-based practice....

Ophthalmology assessment using Revised Bloom’s Taxonomy

Bloom’s Taxonomy is a hierarchical list of attributes and skills that facilitates teachers to effectively teach, whilst concurrently enabling learners to effectively learn. It was first developed in 1956 by Benjamin Bloom, an educational psychologist along with a team of...

Preparing to sit the FRCOphth Part 1 as a new FY1: A modern financial, educational and AI-enhanced study guide

One week into my first year as a doctor, buried under a mountain of ward jobs, night shifts and the sheer vertical learning curve of FY1, I decided to challenge myself further: I booked the FRCOphth Part 1 exam. The...

Pigmented paravenous retinochoroidal atrophy

Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...

VISION 2020 LINKS: Retinoblastoma 
in Africa

The VISION 2020 LINKS Programme is part of the ‘VISION 2020: The Right to Sight’ global initiative to eliminate avoidable blindness [1]. The LINKS Programme works with overseas eye departments to help identify priorities and match their priority needs with...