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Neuro-ophthalmology front cover image.

Histopathological changes in rabbit retinitis pigmentosa

1 April 2017 | | EYE - Neuro-ophthalmology | Optic disc, optic nerve, rabbit, retinal ganglion cell, retinitis pigmentosa
The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...
Acta Ophthalmologica cover image.

Climatic droplet keratopathy

1 December 2015 | | EYE - Cornea, EYE - General | UV-B, ascorbate, environment, human, keratopathy
Climatic droplet keratopathy (CDK) is an acquired and potentially handicapping corneal degenerative disease that is highly prevalent in certain rural communities around the world. It predominantly affects males in their 40’s and is known by many other names such as...
Ophthalmic Research journal cover image.

Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

1 October 2014 | | EYE - Cornea, EYE - General
Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...
Experimental Eye Research cover image.

Autophagy in lens mitochondria loss

1 April 2014 | | EYE - Cataract, EYE - Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
British Journal of Ophthalmology cover image.

Corneal suture sample evaluation

1 February 2019 | | EYE - Cornea, EYE - General | cornea, infection, microbiology
This is a prospective study of 35 patients’ suture samples taken from a tertiary cornea clinic, Miami, Florida, with a history of penetrating keratoplasty. The aim is to study the relationship between corneal suture bacteriology, biofilm and the clinical setting,...

Is it NAION… Now what?

3 April 2024 | | EYE - Neuro-ophthalmology
Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

Around 450,000 children disadvantaged by lack of school support for colour blindness

5 December 2024 | colour blindness, eyesight, SEND, education, children, school, book
Around 450,000 children are being failed by the UK education system because they have a special educational need and disability (SEND) that is effectively unrecognised by most schools and local education authorities, an author has warned. Supporting Colour Blindness in...

A practical guide to anisocoria

1 February 2018 | | EYE - Neuro-ophthalmology, EYE - General
Anisocoria means the presence of difference in the size of the right and left pupils. It is a sign of an abnormality in the efferent pathway. The first question facing the ophthalmologist is to ascertain if anisocoria is present or...

What's trending Feb/Mar 2018

1 February 2018 | | EYE - General
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. We are officially in 2018. New year, new you. The clock starts to turn to midnight and suddenly the excess...

A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia

1 December 2013 |
An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...

Supporting optical professions throughout the pandemic

1 December 2020
A letter has been released to go to all optical professionals on behalf of the professional bodies and government bodies responsible for ophthalmic dispensing and optometry.

Scotland's Bottle Deposit Return Scheme – have visually impaired people even been considered?

31 May 2023 | vision impairment, Sight Scotland, Sight Scotland Veterans
Sight Scotland and Sight Scotland Veterans have welcomed the delay to the Bottle Deposit Return Scheme and are urging the Scottish Government to use this time to consider the implications it will have for visually impaired people.