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Visual acuity after cataract surgery in AMD patients

The data from this study are obtained from the Age-Related Eye Disease Study (AREDS) 2 and analysed to evaluate if cataract surgery benefits patients with concurrent age-related macular degeneration (AMD). The AREDS 2 was a five year, prospective, multi-centre randomised...

Characteristics of Charles Bonnet syndrome in patients with neovascular AMD

This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...

The last three patients: general medicine (Patient Two)

For the second reflection in this series (see Patient One here), Professor Jonathan Rees recounts his experiences of the last patient he saw as a medical registrar, telling the tragic story of a young man’s death and the risks that...

Clinicopathologic factors and survival in patients with sebaceous carcinoma of eyelid

This is a population-based analysis performed to evaluate the prognostic factors and survival of patients with sebaceous carcinoma of the eyelid. Patients with eyelid sebaceous carcinoma from 1973-2013 were identified from the Surveillance, Epidemiology and End Results (SEER) database and...

Congenital nasolacrimal duct obstruction in patients with craniofacial abnormalities

This is a retrospective study including 1998 patients over a period of 10 years. Of this number, 41 patients were identified as having a craniofacial abnormality and congenital nasolacrimal duct obstruction (CNLDO) (23.1 per 10,000 live births). Interestingly the most...

The last three patients: general practice (Patient One)

Professor Jonathan Rees is an Emeritus Professor of Dermatology at the University of Edinburgh (2020). He held the Grant Chair of Dermatology in Edinburgh from 2000 to 2020, and before that the Chair of Dermatology in Newcastle from 1992 to...

Meibomian gland dropout in patients with dry eyes

In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...

Is laser refractive surgery safe for patients taking isotretinoin?

This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...

Cataract surgery in patients with Vogt-Koyanagi-Harada

This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...

Is serum ACE useful in diagnosing sarcoidosis in uveitis patients?

This retrospective clinical notes review assesses whether serum angiotensin converting enzyme (ACE) is useful in the diagnosis of sarcoidosis in patients presenting with uveitis. There were 1035 consecutive subjects presenting with uveitis as part of baseline investigations had a serum...

Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis

This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....

The last three patients: dermatology (Patient Three)

For the third and final reflection in this series (see Part 1 and Part 2), Professor Jonathan Rees recounts his experience of a patient with cancer who was failed by the NHS, and how their inadequate treatment illuminates some issues...