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Could midbrain volume on MRI be used to guide diagnosis of progressive supranuclear palsy?

The authors present a cohort study, of patients with a likely diagnosis of progressive supranuclear palsy (PSP) using a combination of prospective assessment and retrospective review. The cohort comprised of 14 patients; the data for six patients was obtained through...

Dry eyes after photorefractive keratoplasty

This study examined changes in tear break up time (TBUT), Schirmer test, tear osmolarity and dry eye questionnaire (OSDI) score from prior to photorefractive keratoplasty (PRK), to two months and four months postoperatively. Fifty eyes of 25 patients were examined....

Is laser refractive surgery safe for patients taking isotretinoin?

This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...

Prostaglandin-associated periorbitopathy

This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...

AMD and visceral fat and pro-inflammatory factors

Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...

Topography-guided photorefractive keratectomy in the treatment of corneal scarring

This study reports the outcome of topography-guided photorefractive keratectomy (TG-PRK) in the treatment of patients with corneal scarring. A retrospective case series including six eyes of six patients with corneal scarring and irregular astigmatism who underwent topography guided PRK. The...

Penetrating keratoplasties in infants

This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...

Contrast sensitivity after laser corneal surgery

This study group compared contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimised photorefractive keratectomy (PRK) or laser-assisted in situ keratomileusis (LASIK) for the treatment of myopia or myopic astigmatism 12 months after surgery. This was a prospective, randomised clinical trial,...