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Journal of Neuro-Ophthalmology cover image.

Exploring the potential of neurodegenerative disease screening within age-related eye disease research

3 August 2023 | | EYE - Neuro-ophthalmology
The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...
Ophthalmologica journal cover image.

OCT prognostic factors in AMD patients with peripapillary choroidal neovascularisation

3 August 2023 | | EYE - Vitreo-Retinal
In this retrospective study the authors aimed to investigate the correlation between optical coherence tomography (OCT) findings and visual acuity outcomes after treatment with intravitreal bevacizumab (IVB) injections for age-related macular degeneration (AMD) patients with peripapillary choroidal neovascularisation (PPCNV). Data...
Seminars in Ophthalmology journal front cover image.

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

6 February 2024 | | EYE - Vitreo-Retinal | Internal limiting membrane, internal limiting membrane insertion technique, inverted internal limiting membrane flap technique, large macular hole; meta-analysis
This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...
Ophthalmologica journal cover image.

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

1 November 2024 | | EYE - Vitreo-Retinal
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Macular imagery: observing the visual sensations pre- and post-Jetrea injections

25 September 2021 | | EYE - Vitreo-Retinal, EYE - General
A 63-year-old woman, a professional painter, was diagnosed with vitreomacular traction (VMT) in 2017. She had a history of metamorphopsia, drop in visual acuity (VA) in the left eye (6/6 in the RE; 6/18 in the LE), foveal vitreomacular traction...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Moorfields surgeons save the sight of 24 wounded Bangladeshi students

30 April 2025 | international, politics, conflict, trauma, Bangladesh, emergency
Moorfields Eye Hospital consultant ophthalmologists Mahi Muqit and Niaz Islam were invited to Dhaka by Bangladesh’s interim government to help 120 patients with bullet wounds to their eyes. Their injuries were a result of their involvement in protests against the...

Internuclear ophthalmoplegia: a case study

3 June 2024 | | EYE - General
A 44-year-old patient presents with binocular, mostly horizontal diplopia when fixating on moving objects. This has been ongoing for approximately five years. He is known to have multiple sclerosis and had an episode of optic neuritis six years prior in...

The madarosis mystery: unravelling the clues to a host of health issues

4 October 2023 | | EYE - Cornea
Eyelash madarosis is a medical condition characterised by the loss of eyelashes caused by the destruction of hair follicles. It can range from a few missing lashes to a complete absence of lashes on the eyelids. This condition can be...

Pituitary adenoma causing compression of the optic chiasm

1 April 2019 | | EYE - Neuro-ophthalmology, EYE - General
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...

The bionic eye – behind the headlines

1 October 2016 | | EYE - Oculoplastic, EYE - Orbit
Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Across the globe and into the world of international eye grading

4 October 2023 | | EYE - Imaging
Decades have passed and the influence of analysing fundus images by grading consultants and retinal image specialists has grown worldwide. Their job is to specialise in assessing hundreds of diagnosed eye disease disorders and to read thousands of eye images,...