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Pituitary tumours: why are they so often missed?

Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Diagnosis of ocular tuberculosis

This review article provides an update on the methods diagnosing ocular tuberculosis (TB), the difficulties in making the diagnosis and makes recommendations to a more accurate diagnosis by combining the available diagnostic tests. Today ocular TB remains a presumptive clinical...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Congenital and paediatric cataract: Advances in diagnosis and management

Congenital and paediatric cataracts are relatively rare, although prevalence varies significantly between countries, influenced by factors such as nutrition, immunisation policy and population genetics [1]. In the UK, around 3–4 of every 10,000 babies are born with cataracts. It’s a...

Upper eyelid ulceration as a presenting sign of frontal sinus mucocele

Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...

Good news: new study links moderate wine consumption to lower risk of cataract surgery

An observational study published today in Ophthalmology (the journal of the American Academy of Ophthalmology) indicates that low to moderate alcohol consumption is associated with a lower risk of requiring surgery for cataracts, although the nature of the study means it does not definitively prove a direct causal effect.

Macular imagery: observing the visual sensations pre- and post-Jetrea injections

A 63-year-old woman, a professional painter, was diagnosed with vitreomacular traction (VMT) in 2017. She had a history of metamorphopsia, drop in visual acuity (VA) in the left eye (6/6 in the RE; 6/18 in the LE), foveal vitreomacular traction...

Neonatal hypoxic ischaemic encephalopathy with imaging abnormalities in the occipital lobe – how to counsel the parents

Case A baby boy, with a background of intrauterine growth restriction, was born at 37 weeks and three days gestation via forceps delivery. The baby was born in poor condition, with low heart rate, poor respiratory rate, poor colour and...

Pituitary tumours: why are they so often missed?

Part 1: Introduction, historical background and Edinburgh connections (see also Part 2 and Part 3) Is there any ophthalmologist who has not missed a pituitary tumour? Hopefully this article will help those currently in practice to avoid such an embarrassment,...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Binocular single vision (BSV)

Introduction In this article I will try to summarise some of the definitions, tests and assessments performed in the strabismus clinic to assess patient binocular potential. This is a key feature of strabismus assessment, especially in adults, and it will...