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Brolucizumab in age-related macular degeneration, HAWK Study
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
Changing operating room practices: the effect on postoperative endophthalmitis rates following cataract surgery
This is a retrospective clinical registry study from India of 85,552 cataract surgery patients; group 1 (56,551 patients from January-March 2020) and group 2 (29,011 patients from May-August 2020). Group 1’s patients were ungowned, surgical gloves were disinfected but not...
Multidrug-resistant keratitis: challenging yet manageable
This is a retrospective review of all patients’ records from a tertiary referral centre in India from January 2018 to December 2019, who had corneal scrapings for direct smear and culture sensitivity. Those cases where the organisms were diagnosed to...
Ocular findings in children with myasthenia
This is a retrospective audit of paediatric myasthenic patients presenting to Great Ormond Street (GOSH) between January 2016 and January 2020. During this period there were 49 children, including 27 with juvenile myasthenia (JMG) and the rest as congenital myasthenia...
Macular measurements for amblyopic eyes
This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06...
Disc-fovea angle measurements for objective cyclotorsion review
The author measured the disc-fovea angle (DFA) in 249 healthy people (81 male, 168 female) as part of a retrospective study of 44 to 70-year-old adults. These were grouped as (1) aged 44 / 45 years, (2) aged 59-70 years,...
Ocular motility parameters in phakic and pseudophakic older people
The aim of this study was to compare the extent of phoria, strabismus and convergence of pseudophakic vs phakic people in an elderly population. The study was part of the Tehran Geriatric Eye Study (TGES). Of 3791 invitees, 3310 participated...
Case reports of neuro-visual consequences of mild COVID-19 in children
Neuro-visual involvement has been reported in numerous patients with severe SARS-CoV-2 disease, mainly among adult patients. In children, such involvement has been reported in rare cases, often in those presenting with severe forms of COVID-19. The aim of this work...
Tutopatch® in surgical management of third nerve palsy
his study evaluates the benefit of using Tutopatch® to elongate the extraocular muscles in patients with third nerve palsy who have residual strabismus after unsuccessful surgery and no other surgical options considered to be appropriate. The study included nine patients...
Bromfenac versus betamethasone in diabetic macular oedema
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
Ophthalmic presentations and outcomes in Erdheim-Chester disease
This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...
